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Acetaminothiophen

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Identification
Molecular formula
C9H11NO1S1
CAS number
4865-61-2
IUPAC name
N-[3-(sulfanylmethyl)phenyl]acetamide
State
State
Acetaminothiophen is a solid at room temperature.
Melting point (Celsius)
168.00
Melting point (Kelvin)
441.00
Boiling point (Celsius)
453.00
Boiling point (Kelvin)
726.00
General information
Molecular weight
181.25g/mol
Molar mass
181.2460g/mol
Density
1.1692g/cm3
Appearence

Acetaminothiophen typically appears as a crystalline powder. The color can range from white to a pale yellow, depending on the purity and conditions of storage.

Comment on solubility

Solubility of N-[3-(sulfanylmethyl)phenyl]acetamide

N-[3-(sulfanylmethyl)phenyl]acetamide is a compound that exhibits intriguing solubility characteristics. Understanding its solubility is crucial for applications in pharmaceuticals and material science. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is likely to demonstrate variable solubility in different solvents, primarily due to the presence of the sulfanyl group, which can interact with polar solvents.
  • Polar vs. Non-Polar solvents: It is expected to be more soluble in polar aprotic solvents like dimethyl sulfoxide (DMSO) than in non-polar solvents such as hexane.
  • Hydrogen Bonding: The presence of a carbonyl group (from the acetamide moiety) may enable it to participate in hydrogen bonding, further influencing its solubility profile.
  • pH Sensitivity: The solubility can also be affected by the pH of the solution, as ionization of the amide can occur under certain conditions, impacting its overall solubility.

It is often stated that "like dissolves like," which is particularly relevant for N-[3-(sulfanylmethyl)phenyl]acetamide. Thus, its solubility is enhanced in environments that can mimic its structural characteristics.

In conclusion, while specific solubility data for N-[3-(sulfanylmethyl)phenyl]acetamide may require empirical determination, understanding the principles of solubility can guide further research and application of this compound.

Interesting facts

Interesting Facts about N-[3-(sulfanylmethyl)phenyl]acetamide

N-[3-(sulfanylmethyl)phenyl]acetamide is a fascinating compound that showcases the intricate relationship between structure and function in organic chemistry. Here are some intriguing aspects of this compound:

  • Functional Groups: This compound features a well-defined structure comprising an acetamide group linked to a phenyl ring with a sulfanylmethyl substituent. The presence of these functional groups plays a crucial role in its chemical behavior and potential applications.
  • Biological Relevance: Compounds similar to N-[3-(sulfanylmethyl)phenyl]acetamide often exhibit biological activity. Many sulfenamide derivatives have been researched for their potential therapeutic effects, including antimicrobial and anti-inflammatory properties.
  • Synthesis Techniques: The synthesis of this compound can be achieved through various methodologies, including nucleophilic substitution reactions or coupling reactions. Understanding these methods aids in the design of related compounds with tailored properties.
  • Role of Sulfur: The sulfanylmethyl group is particularly noteworthy, as sulfur-containing compounds are known for their unique reactivity and ability to form diverse bonds. This can lead to exciting chemical transformations useful in synthesis.
  • Research Potential: As scientists continue to explore the potential of structures like N-[3-(sulfanylmethyl)phenyl]acetamide, it offers a promising avenue for developing novel materials, pharmaceuticals, and agrochemicals.

In summary, N-[3-(sulfanylmethyl)phenyl]acetamide is more than just a simple chemical formula; it represents a convergence of functionalities and applications that can potentially be harnessed in various fields of research and industry. Its exploration embodies the spirit of creativity and innovation inherent in the realm of chemistry.

Synonyms
ANILINE, N-ACETYL-3-METHYLTHIO-
N-Acetyl-m-methylthioaniline
NSC 157358
N-Acetyl-3-methylthio-aniline
UD0476C909
BRN 2087488
UNII-UD0476C909
NSC-157358
N-(3-(MERCAPTOMETHYL)PHENYL)ACETAMIDE
ACETAMIDE, N-(3-(MERCAPTOMETHYL)PHENYL)-
4-13-00-01010 (Beilstein Handbook Reference)
635-096-9
aniline, n-acetyl-3-(methylthio)-
N-[3-(sulfanylmethyl)phenyl]acetamide
AKOS015898715
D91521