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Sipatrigine

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Identification
Molecular formula
C16H10Cl2N2
CAS number
152946-68-4
IUPAC name
N-(3,4-dichlorophenyl)-1-(1H-indol-3-yl)methanimine
State
State

At room temperature, Sipatrigine is generally in a solid state.

Melting point (Celsius)
238.50
Melting point (Kelvin)
511.65
Boiling point (Celsius)
490.00
Boiling point (Kelvin)
763.15
General information
Molecular weight
335.17g/mol
Molar mass
335.1700g/mol
Density
1.4890g/cm3
Appearence

Sipatrigine typically appears as a solid, crystalline powder. Depending on the batch and level of purity, it can range in color from white to off-white.

Comment on solubility

Solubility of N-(3,4-dichlorophenyl)-1-(1H-indol-3-yl)methanimine

N-(3,4-dichlorophenyl)-1-(1H-indol-3-yl)methanimine is known for its intriguing solubility characteristics, which can significantly influence its applications in various fields, particularly in pharmaceutical formulations. Understanding its solubility is essential for optimizing its performance in biological systems.


Key Points on Solubility:

  • Solvent Dependency: The solubility of this compound can vary drastically depending on the solvent used. For example, it is generally more soluble in organic solvents, such as ethanol and dimethyl sulfoxide (DMSO), than in polar protic solvents like water.
  • Temperature Sensitivity: Increased temperature typically enhances solubility, allowing for greater dissolution in organic solvents, which may be crucial during synthesis and formulation processes.
  • pH Influence: The solubility might be affected by the pH of the solution, highlighting the importance of optimizing conditions for maximal solubility based on the intended use.
  • Crystal Form Variability: Different polymorphic forms of the compound can exhibit distinct solubility profiles, which can impact drug formulation strategies.

In conclusion, understanding the solubility of N-(3,4-dichlorophenyl)-1-(1H-indol-3-yl)methanimine is crucial for its effective utilization. As noted, its solubility varies with solvent type, temperature, and pH, and can also change based on its crystal form. Researchers must consider these factors to enhance the compound's application in real-world scenarios.

Interesting facts

Interesting Facts about N-(3,4-Dichlorophenyl)-1-(1H-indol-3-yl)methanimine

N-(3,4-Dichlorophenyl)-1-(1H-indol-3-yl)methanimine is a fascinating compound that represents a convergence of synthetic and natural chemistry. Here are some intriguing aspects of this molecule:

  • Dual Nature: This compound features both chlorophenyl and indole moieties, showcasing the blending of synthetic and naturally occurring components.
  • Biological Importance: Indole derivatives are well-known in biochemical research and have been identified as key players in various biological processes, including potential anti-cancer properties.
  • Potential Applications: The structure of this compound may contribute to research in pharmaceuticals, particularly in the development of new therapeutic agents targeting diseases like cancer and infections.
  • Research Interest: Given the strategic placement of the dichlorophenyl group, studies often explore how the substituents influence biological activity and molecular interactions.
  • Mechanistic Studies: The compound's structure allows chemists to investigate reaction mechanisms and the effects of substituents on reactivity and stability.

Such compounds open up avenues for innovation in medicinal chemistry and materials science. As researchers delve deeper into its properties and potential implications, this compound could play a pivotal role in advancing our understanding of complex biological interactions.

In the words of a notable chemist, **"Each compound tells a story of molecular design and functional evolution."** This statement rings true for N-(3,4-Dichlorophenyl)-1-(1H-indol-3-yl)methanimine, which stands at the crossroads of chemistry, biology, and medicine.

Synonyms
(1E)-1-(3,4-dichlorophenyl)-2-indol-3-yl-1-azaethene
BRN 1469732
3-(N-(3,4-Dichlorophenyl)formimidoyl)indole
22394-34-9
INDOLE, 3-(N-(3,4-DICHLOROPHENYL)FORMIMIDOYL)-
TimTec1_000805
CBDivE_002971
HMS1536E13
STK390977
AKOS002927170
ST009502
3,4-dichloro-N-[(E)-1H-indol-3-ylmethylidene]aniline
(3,4-DICHLORO-PHENYL)-(1H-INDOL-3-YLMETHYLENE)-AMINE