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Clomipramine hydrochloride

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Identification
Molecular formula
C19H24ClN3
CAS number
17321-77-6
IUPAC name
[N'-[[(3,4-dichlorophenyl)-[4-(trifluoromethyl)phenyl]methylene]amino]carbamimidoyl]ammonium;chloride
State
State

At room temperature, Clomipramine hydrochloride is in solid state.

Melting point (Celsius)
192.50
Melting point (Kelvin)
465.70
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
351.74g/mol
Molar mass
351.7410g/mol
Density
1.3300g/cm3
Appearence

Clomipramine hydrochloride is a white to off-white crystalline powder.

Comment on solubility

Solubility of N'-[[(3,4-dichlorophenyl)-[4-(trifluoromethyl)phenyl]methylene]amino]carbamimidoyl]ammonium; chloride

The solubility of N'-[[(3,4-dichlorophenyl)-[4-(trifluoromethyl)phenyl]methylene]amino]carbamimidoyl]ammonium; chloride can be quite intriguing due to its complex structure. Factors influencing the solubility of this compound include:

  • Polarity: The presence of chlorine and trifluoromethyl groups affects the overall polarity of the molecule, which in turn impacts its interaction with solvents.
  • Hydrophilicity vs. Hydrophobicity: The ammonium chloride part suggests a certain degree of hydrophilicity, but the bulky aromatic rings can introduce hydrophobic characteristics, potentially limiting solubility in water.
  • Temperature: Like many organic compounds, solubility may increase with temperature due to enhanced molecular movement.
  • Solvent Type: This compound may exhibit different solubility profiles in various solvents. For example, it could be more soluble in polar aprotic solvents compared to water.

Overall, while the structural components may suggest limited solubility in water, it is essential to consider the specific solvents and conditions when evaluating the solubility behavior of this compound. As always, experimental data is invaluable for confirming solubility characteristics.

Interesting facts

Interesting Facts about N'-[(3,4-Dichlorophenyl)-[4-(trifluoromethyl)phenyl]methylene]amino]carbamimidoyl]ammonium;chloride

This compound, with its complex structure, belongs to a fascinating class of chemicals that can exhibit unique properties and applications. Here are some noteworthy aspects:

  • Diverse Applications: Compounds with such chemical architecture may have potential uses in pharmaceuticals, particularly as intermediates in the synthesis of biologically active molecules.
  • Substituent Variability: The presence of both dichlorophenyl and trifluoromethyl substituents significantly alters the electronic character of the compound, while influencing its reactivity and interaction with biological systems.
  • Research Potential: Given its structural attributes, this compound can be a subject of interest in research concerning new drugs or agrochemicals that target specific biological pathways, enhancing selectivity and reducing side effects.
  • Environmental Impact: Understanding compounds like this is crucial in assessing environmental risks, especially considering that some chlorinated and fluorinated compounds have raised concerns due to their persistence in the environment.
  • Mechanistic Insights: Exploring the chemical behavior of this compound can provide deeper insights into mechanisms of action in medicinal chemistry, particularly in understanding how such compounds can bind to specific targets.

In conclusion, this compound exemplifies how intricate chemical structures can lead to a wide range of biological functionalities and highlights the importance of chemical research in developing new materials and pharmaceuticals. As the field of chemistry evolves, compounds like these will continue to contribute to advancements in various scientific realms.