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N'-(3,4-dichlorophenyl)benzohydrazide

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Identification
Molecular formula
C13H10Cl2N2O
CAS number
2767-70-2
IUPAC name
N'-(3,4-dichlorophenyl)benzohydrazide
State
State

At room temperature, N'-(3,4-dichlorophenyl)benzohydrazide is typically found in a solid state. It is stable under standard conditions and must be handled with care due to its chemical properties.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
359.00
Boiling point (Kelvin)
632.15
General information
Molecular weight
282.14g/mol
Molar mass
282.1550g/mol
Density
1.5030g/cm3
Appearence

N'-(3,4-dichlorophenyl)benzohydrazide appears as a crystalline solid. It is usually off-white to beige in color. Its appearance may vary slightly depending on the purity and form (e.g., powdered, crystalline) of the sample.

Comment on solubility

Solubility of N'-(3,4-Dichlorophenyl)benzohydrazide

N'-(3,4-Dichlorophenyl)benzohydrazide, with the chemical formula C13H10Cl2N2O, exhibits intriguing solubility characteristics. Generally, the solubility of a compound is influenced by several factors including its molecular structure, temperature, and the presence of functional groups. In the case of this compound:

  • Hydrophobic Interactions: The presence of the benzene rings and chlorinated substituents contributes to its hydrophobic nature, leading to lower solubility in polar solvents like water.
  • Polar Groups: Despite the hydrophobic traits, the presence of the hydrazide functional group may enhance solubility in some polar organic solvents.
  • Solvent Polarity: It is generally more soluble in less polar organic solvents (e.g., ethanol and methanol) than in water.

In conclusion, while N'-(3,4-dichlorophenyl)benzohydrazide has a rather limited solubility in water due to its molecular structure, it demonstrates better solubility in organic solvents. As said, “the solubility really depends on the solvent used.” Therefore, for practical applications, one must consider choosing the appropriate solvent based on the desired concentration and compatibility.

Interesting facts

Interesting Facts about N'-(3,4-dichlorophenyl)benzohydrazide

N'-(3,4-dichlorophenyl)benzohydrazide is a fascinating compound that plays a significant role in both organic chemistry and medicinal chemistry. Here are some captivating insights:

  • Biological Significance: This compound has attracted attention for its potential pharmacological properties. Researchers have investigated its efficacy in various therapeutic applications, including anti-inflammatory and anti-cancer activities.
  • Synthesis: The synthesis of N'-(3,4-dichlorophenyl)benzohydrazide typically involves a straightforward reaction between hydrazine and the corresponding benzoyl chloride, showcasing the elegance of organic synthetic pathways.
  • Structure-Activity Relationship (SAR): Understanding how structural variations impact biological activity has made hydrazides like this one an interesting focus. The presence of the dichlorophenyl group can significantly influence its reactivity and biological interactions.
  • Research Interest: Due to its potential applications, this compound is often studied in the context of drug discovery, with scientists exploring modifications that could enhance its efficacy and reduce side effects.
  • Environmental Impact: As with many chemical compounds, understanding the environmental pathways and effects of N'-(3,4-dichlorophenyl)benzohydrazide is crucial, particularly in contexts where it might be utilized industrially or pharmacologically.

The study of N'-(3,4-dichlorophenyl)benzohydrazide exemplifies how a simple molecular structure can harbor complex interactions, making it an enduring subject of interest in modern chemistry.

Synonyms
BRN 0665042
BENZOIC ACID, 2-(3,4-DICHLOROPHENYL)HYDRAZIDE
13124-03-3
DTXSID60156976
DTXCID6079467
AKOS000281735
SR-01000398590
SR-01000398590-1