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N-(3,4-dichlorophenyl)hexanamide

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Identification
Molecular formula
C12H15Cl2NO
CAS number
2905-62-6
IUPAC name
N-(3,4-dichlorophenyl)hexanamide
State
State

At room temperature, N-(3,4-dichlorophenyl)hexanamide is generally found in a solid state.

Melting point (Celsius)
72.00
Melting point (Kelvin)
345.15
Boiling point (Celsius)
335.50
Boiling point (Kelvin)
608.70
General information
Molecular weight
274.18g/mol
Molar mass
274.1780g/mol
Density
1.2023g/cm3
Appearence

N-(3,4-dichlorophenyl)hexanamide typically appears as a crystalline solid. Its appearance is characterized by a white to off-white color, depending on purity and the conditions under which it was synthesized and stored.

Comment on solubility

Solubility of N-(3,4-dichlorophenyl)hexanamide

The solubility of N-(3,4-dichlorophenyl)hexanamide can be characterized as moderate, influenced by its unique structural features and functional groups. Here are some points to consider:

  • Polarity: The presence of the 3,4-dichlorophenyl group contributes to the compound's overall polarity, affecting its interactions with solvents.
  • Solvent Compatibility: N-(3,4-dichlorophenyl)hexanamide is likely to be more soluble in organic solvents such as ethanol, acetone, and chloroform, rather than in water, due to hydrophobic interactions from the alkyl chain.
  • Temperature Effects: Solubility can be enhanced at elevated temperatures, which is a common behavior for many organic compounds.
  • Ionization Potential: The amide functional group presents a potential for hydrogen bonding, which may result in some degree of solubility in polar solvents, but overall, this is limited.

In summary, while N-(3,4-dichlorophenyl)hexanamide exhibits some solubility in polar solvents, its overall solubility is better suited for non-polar to mildly polar organic solvents. Thus, solvents such as ethanol and acetone are recommended for effective dissolution.

Interesting facts

Interesting Facts about N-(3,4-dichlorophenyl)hexanamide

N-(3,4-dichlorophenyl)hexanamide, often associated with various research applications, is a compound that brings forth both intrigue and potential in the field of chemistry. Here are some noteworthy aspects:

  • Pharmaceutical Relevance: This compound has been studied for its potential pharmaceutical applications, especially in the design of novel therapeutic agents. With its unique molecular structure, it offers a basis for exploring new drug syntheses.
  • Halogen Substitution: The presence of chlorine atoms in the structure plays a critical role in enhancing the compound’s biological activity. Halogen substitution can significantly influence the properties and reactivity of organic molecules.
  • Structure Activity Relationship (SAR): Researchers often examine the SAR of compounds like N-(3,4-dichlorophenyl)hexanamide to understand how modifications in the molecular structure impact their effectiveness and safety profiles.
  • Environmental Impact: The environmental stability of such amides raises discussions regarding their biodegradation and potential ecological footprint, leading to further studies in environmental chemistry.
  • Future Research Directions: Continued investigations into this compound could lead to exciting discoveries in medicinal chemistry, as scientists look to optimize activity while minimizing side effects.

In conclusion, N-(3,4-dichlorophenyl)hexanamide not only serves as a testament to the complexity and diversity of organic compounds, but it also reflects the profound impact that chemical modifications can have on biological functions. As research evolves, the implications of such compounds in medicinal chemistry remain a key area of exploration.

Synonyms
N-(3,4-dichlorophenyl)hexanamide
3',4'-Dichlorocaproanilide
CHEMBL48905
SCHEMBL1876366
UHNACMYDEPKBKS-UHFFFAOYSA-N
AKOS003463236