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N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide

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Identification
Molecular formula
C8H16N2O4
CAS number
2162-74-5
IUPAC name
N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide
State
State

At room temperature, N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide is in a solid state. Its stable structure makes it handleable under typical laboratory conditions without special precautions.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
205.23g/mol
Molar mass
205.2250g/mol
Density
1.2400g/cm3
Appearence

N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide is typically a white to off-white crystalline solid. It is known for its water solubility and offers a bitter taste.

Comment on solubility

Solubility of N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide (C8H16N2O4)

N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide is an intriguing compound due to its unique structure and functional groups that significantly influence its solubility characteristics. The presence of multiple hydroxyl (-OH) groups in its structure enhances its polarity, which generally increases solubility in polar solvents. Here are some key points regarding its solubility:

  • In Water: The hydroxyl groups make this compound likely soluble in water, which is a polar solvent. The ability to form hydrogen bonds with water molecules enhances its solubility.
  • In Organic Solvents: N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide may exhibit limited solubility in non-polar organic solvents like hexane or benzene, due to its polar characteristics.
  • pH Dependence: The solubility may also vary with pH. Under acidic or basic conditions, the ionization of functional groups could further affect solubility.
  • Comparison with Derivatives: Compounds with similar structures often show differing solubility profiles; hence, it's beneficial to consider its analogs for comparison.

In summary, N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide is expected to be *substantially soluble* in polar solvents like water, while showing *limited solubility* in non-polar solvents. Understanding these solubility dynamics is essential for further applications and research involving this compound.

Interesting facts

Exploring N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide

N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide is a fascinating compound with a variety of applications and properties that intrigue scientists and students alike.

Key Highlights:

  • Pharmaceutical Potential: This compound has garnered attention due to its potential use in the development of various therapeutic agents, particularly for neurodegenerative diseases.
  • Bioactivity: The presence of multiple hydroxyl (-OH) groups suggests enhanced water solubility and the potential for diverse interactions with biological molecules, potentially influencing its pharmacological effects.
  • Structure-Activity Relationship (SAR): Understanding how modifications to the piperidine backbone affect bioactivity can provide deeper insights into drug design.
  • Hydroxyl Groups: The tri-hydroxy substitution indicates that this molecule may be able to donate and accept protons easily, a key factor in biochemical interactions.

Quote to Reflect On:

"The beauty of chemistry lies in the intricate dance of atoms and the relationships they form."

This compound exemplifies this beauty. Its structural elements not only define its physical characteristics but also dictate its biological behavior. In addition, research continues to explore its role in synthesizing more complex pharmacological compounds, which can pave the way for new treatments. The ongoing study of N-[(3,4,5-trihydroxy-2-piperidyl)methyl]acetamide serves as a reminder of the innovative and evolving nature of medicinal chemistry.

Synonyms
AB05831
2-ADN; DGJNAc