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Bupropion

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Identification
Molecular formula
C13H18N2O
CAS number
34841-39-9
IUPAC name
N-[4-(1-piperidyl)but-2-ynyl]butanamide
State
State

At room temperature, bupropion is in a solid state. It is generally found in tablet form when used in pharmaceuticals. Its physical state, combined with its molecular properties, makes it suitable for oral administration.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
370.80
Boiling point (Kelvin)
644.00
General information
Molecular weight
239.32g/mol
Molar mass
239.7210g/mol
Density
1.1800g/cm3
Appearence

Bupropion typically appears as a white crystalline powder. It is odorless and has a bitter taste. It is relatively stable under standard conditions and exhibits minor hygroscopic properties, meaning it can absorb moisture from the air to a small extent.

Comment on solubility

Solubility of N-[4-(1-piperidyl)but-2-ynyl]butanamide

The solubility of N-[4-(1-piperidyl)but-2-ynyl]butanamide in various solvents is influenced by its chemical structure and functional groups. Understanding its solubility is essential for applications in pharmaceuticals and materials science. Here are some key points to consider:

  • Polar and Non-Polar Solvents: N-[4-(1-piperidyl)but-2-ynyl]butanamide is expected to be more soluble in polar solvents due to the presence of the amide functional group, which can engage in hydrogen bonding.
  • Hydrogen Bonding: The amide group facilitates interactions with water, enhancing its solubility in aqueous solutions.
  • Temperature Dependence: Like many organic compounds, the solubility of this compound can vary significantly with temperature; increasing temperature may enhance solubility.
  • Influence of pH: The solubility may also depend on the pH of the solution, as protonation of the nitrogen in the piperidine ring could alter solubility characteristics.

In summary, N-[4-(1-piperidyl)but-2-ynyl]butanamide demonstrates solubility predominantly in polar solvents, influenced by factors such as temperature and pH. As the saying goes, "solubility is the key to its utility" in practical applications, underscoring the importance of understanding this property for effective utilization.

Interesting facts

Exploring N-[4-(1-piperidyl)but-2-ynyl]butanamide

N-[4-(1-piperidyl)but-2-ynyl]butanamide is a fascinating compound that belongs to the category of amides. The unique structure of this compound leads to various interesting properties and potential applications. Here are some intriguing aspects:

  • Pharmaceutical Potential: Amides like this one are often studied for their biological activity. The piperidine ring in this compound may contribute to its interaction with biological targets, making it a candidate for drug development.
  • Structural Diversity: The combination of the piperidyl group and the but-2-ynyl moiety lends itself to diverse chemical functionalities. This unique structural features offer avenues for the synthesis of other complex molecules.
  • Reactivity: The triple bond in the but-2-ynyl group introduces interesting reactivity, allowing for various functionalization options that can lead to new compounds with unique properties.
  • Research Interest: Compounds featuring nitrogen heterocycles, such as piperidine-based structures, are currently in the spotlight for medicinal chemistry research. Scientists are exploring their potential in treating neurological disorders among others.

As one might say in the field of chemistry: "Structure dictates function." The intricate architecture of N-[4-(1-piperidyl)but-2-ynyl]butanamide exemplifies how minor changes in molecular structure can lead to significant differences in activity and application possibilities.

Overall, N-[4-(1-piperidyl)but-2-ynyl]butanamide is a prime example of how organic chemistry intertwines with pharmaceuticals, making it a worthy subject of study for chemists and biochemists alike.