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Olanzapine

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Identification
Molecular formula
C17H20N4O1
CAS number
132539-06-1
IUPAC name
N-[4-[2-(dimethylamino)ethylamino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide
State
State

Olanzapine is typically in a solid state at room temperature. It is available as a powder or crystalline solid, and is further processed into tablets for pharmaceutical applications. In its natural solid state, it is relatively stable and can be safely handled under standard conditions.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
413.60
Boiling point (Kelvin)
686.75
General information
Molecular weight
312.44g/mol
Molar mass
312.4440g/mol
Density
0.4000g/cm3
Appearence

Olanzapine appears as a yellow crystalline solid. It is typically found in the form of tablets for medication use, often yellow or white depending on the formulation and manufacturing processes. The solid form may be either crystalline or amorphous, but in the medical field, olanzapine is generally used in solid tablet forms.

Comment on solubility

Solubility of N-[4-[2-(dimethylamino)ethylamino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide

N-[4-[2-(dimethylamino)ethylamino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide is a complex compound that exhibits interesting solubility characteristics. Understanding its solubility profile is crucial for various applications, including pharmaceutical and chemical processes.

Factors Affecting Solubility

The solubility of this compound can be influenced by:

  • Polarity: The presence of polar functional groups like the amide and dimethylamino groups can enhance solubility in polar solvents such as water.
  • Hydrophobic Interactions: The cycloheptatriene moiety may introduce some hydrophobic character, making the compound less soluble in water but potentially soluble in organic solvents.
  • pH Level: The solubility may vary with changes in pH, especially due to the protonation of the amino groups, which can enhance water solubility.

General Solubility Observations

Considering these factors, we can summarize the solubility expectations:

  • This compound is likely to be moderately soluble in water.
  • It may show higher solubility in organic solvents like ethanol or dimethyl sulfoxide (DMSO).
  • As with many organic compounds, temperature can also play a role, with increased temperatures often leading to higher solubility.

In conclusion, the solubility of N-[4-[2-(dimethylamino)ethylamino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide is influenced by its molecular structure and the surrounding environment, making it a subject of interest for further investigation.

Interesting facts

Interesting Facts About N-[4-[2-(Dimethylamino)ethylamino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide

N-[4-[2-(dimethylamino)ethylamino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide, often referred to by its abbreviated form, is a fascinating compound with significant implications in both the pharmaceutical and chemical realms. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: This compound belongs to a class of chemicals that are being explored for their potential as therapeutic agents. Studies suggest that compounds similar to this one may exhibit antitumor and anti-inflammatory properties, making them of interest to researchers in cancer treatment.
  • Structural Complexity: The presence of the cyclohepta-triene structure combined with a dimethylamino group adds to the compound's complexity. Such structures can lead to interesting stereochemistry and unique interactions, which are crucial in understanding the compound's mechanism of action.
  • Synthetic Routes: The synthesis of this compound can involve multiple steps, often starting from simpler organic molecules. Chemists often engage in optimizing reaction conditions to improve yields and purity.
  • Interdisciplinary Applications: Beyond its potential medical applications, compounds with similar frameworks might find utility in materials science, enhancing the design of new organic materials or catalysts.
  • Research Impact: Scholars have dedicated extensive research to compounds with similar structural characteristics, often finding them pivotal in developing new classes of substances that can overcome the limitations of existing drugs.

Overall, N-[4-[2-(dimethylamino)ethylamino]-5-oxo-cyclohepta-1,3,6-trien-1-yl]acetamide is not only a compound of chemical interest but also a stepping stone towards new therapeutic modalities. As research advances, this compound may illuminate new pathways in both organic chemistry and medicinal research.

Synonyms
15499-07-7
BRN 2742568
Acetamide, N-(4-((2-(dimethylamino)ethyl)amino)-5-oxo-1,3,6-cycloheptatrien-1-yl)-
2-(BETA-DIMETHYLAMINOETHYLAMINO-5-ACETAMIDO)TROPONE
DTXSID40165768
N-(4-((2-(Dimethylamino)ethyl)amino)-5-oxo-1,3,6-cycloheptatrien-1-yl)acetamide
N-[4-[[2-(Dimethylamino)ethyl]amino]-5-oxo-1,3,6-cycloheptatrien-1-yl]acetamide
DTXCID5088259
N-[4-[2-(dimethylamino)ethylamino]-5-oxocyclohepta-1,3,6-trien-1-yl]acetamide