Skip to main content

Acetamide, N-[4-(2-hydroxyethylsulfonyl)phenyl]-

ADVERTISEMENT
Identification
Molecular formula
C10H13NO4S
CAS number
88-04-0
IUPAC name
N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide
State
State

At room temperature, N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide is in a solid state, typically found in crystalline form.

Melting point (Celsius)
151.50
Melting point (Kelvin)
424.60
Boiling point (Celsius)
326.90
Boiling point (Kelvin)
600.00
General information
Molecular weight
229.28g/mol
Molar mass
229.2630g/mol
Density
1.3720g/cm3
Appearence

N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide is typically observed as a white to off-white crystalline powder. Its texture is generally fine, making it easy to handle in laboratory settings.

Comment on solubility

Solubility of N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide

N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide is a compound that exhibits notable solubility characteristics. Understanding its solubility is crucial for its application in various fields, particularly in pharmaceuticals and organic synthesis.

  • Solvent Behavior: This compound tends to dissolve well in polar solvents such as water and methanol due to the presence of the sulfonyl and hydroxyl functional groups.
  • Hydrogen Bonding: The hydroxyl group (-OH) facilitates hydrogen bonding with water molecules, enhancing its solubility in aqueous environments.
  • Temperature Influence: As with many organic compounds, an increase in temperature can lead to increased solubility. This is particularly relevant when considering solvent selection during synthesis or formulation.

In practice, the solubility of N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide can be summarized as:

  1. Highly soluble in polar solvents.
  2. Poorly soluble in non-polar solvents.

This solubility profile is instrumental when considering the compound’s behavior in biological systems, making it an interesting subject for further study and application. As always, it is essential to test solubility under specific conditions to ensure accurate and useful data.

Interesting facts

Interesting Facts about N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide

N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide is a fascinating compound with various applications and intriguing properties. Below are some interesting aspects of this chemical:

  • Pharmaceutical Relevance: This compound may have significant pharmacological potential. Its structure hints at possible use in medicinal chemistry, particularly in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs).
  • Functional Groups: The presence of a sulfonyl group along with a hydroxyethyl moiety contributes to its chemical behavior. Such groups can enhance the solubility and reactivity, potentially leading to improved biological activity.
  • Structural Importance: The acetamide moiety in the structure is essential for modulating the interaction with biological targets. This makes it an attractive candidate in drug development pathways.
  • Synthetic Pathways: The synthesis of N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide can involve various methods, including nucleophilic substitutions and coupling reactions, reflecting the creativity needed in organic synthesis.
  • Research Potential: Ongoing studies can explore its efficacy in various biological assays, potentially revealing new therapeutic applications.

As we continue to dive deeper into the world of chemical compounds like N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide, we uncover the myriad ways these substances can impact our understanding of biology and medicine.

Synonyms
N-(4-((2-HYDROXYETHYL)SULFONYL)PHENYL)ACETAMIDE
Acetamide, N-[4-[(2-hydroxyethyl)sulfonyl]phenyl]-
N-{4-[(2-hydroxyethyl)sulfonyl]phenyl}acetamide
EINECS 248-433-6
p-Acetaminofenyl-2-hydroxyethylsulfon [Czech]
4'-(2-Hydroxyethylsulfonyl)acetanilide
BRN 2742434
p-Acetaminofenyl-2-hydroxyethylsulfon
p-Acetaminofenyl-beta-hydroxyethylsulfon [Czech]
p-Acetaminofenyl-beta-hydroxyethylsulfon
Acetamide, N-(4-((2-hydroxyethyl)sulfonyl)phenyl)-
DTXSID4067305
EC 248-433-6
3-13-00-01276 (Beilstein Handbook Reference)
ACETANILIDE, 4'-(2-HYDROXYETHYLSULFONYL)-
N-(4-((2-Hydroxyethyl)sulphonyl)phenyl)acetamide
N-[4-[(2-hydroxyethyl)sulphonyl]phenyl]acetamide
N-[4-[(2-Hydroxyethyl)sulfonyl]phenyl]acetamide
RefChem:551713
DTXCID4037667
248-433-6
27375-52-6
N-[4-(2-hydroxyethylsulfonyl)phenyl]acetamide
N-[4-(2-hydroxyethanesulfonyl)phenyl]acetamide
MFCD00454261
Cambridge id 5255854
TimTec1_001025
Oprea1_192045
SCHEMBL5711952
XIICKRYAUAVEQS-UHFFFAOYSA-N
HMS1536O13
BBL001180
STK368410
AKOS005444230
NCGC00174873-01
ST009513
VS-00837
NS00005790
N-[4-(2-hydroxyethylsulfonyl)phenyl]ethanamide
375H526
A819039
BRD-K64632684-001-01-9