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Procardazine

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Identification
Molecular formula
C14H21N3O4S
CAS number
22071-41-0
IUPAC name
N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide
State
State

At room temperature, N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide is a solid compound. It is stable under standard conditions, making it manageable in typical laboratory environments.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.00
Boiling point (Celsius)
489.00
Boiling point (Kelvin)
762.00
General information
Molecular weight
327.40g/mol
Molar mass
327.3950g/mol
Density
1.3400g/cm3
Appearence

N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide is typically found as a crystalline solid. The appearance can vary from a white to an off-white powder.

Comment on solubility

Solubility of N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide

The solubility of N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide, also referred to as a sulfonamide derivative, can be affected by multiple factors. Some key points regarding its solubility include:

  • Solvent Type: This compound tends to have varying solubility in different solvents. Generally, it is more soluble in polar solvents like water and DMSO.
  • Effect of pH: The solubility may increase in acidic or basic environments due to the ionization of different functional groups within the molecule. This can lead to better interaction with the solvent.
  • Temperature Influence: Raising the temperature often enhances solubility; thus, heating the solvent might be beneficial for dissolving the compound efficiently.
  • Hydrogen Bonding: The presence of functional groups capable of forming hydrogen bonds, such as the morpholine and sulfonamide moieties, can increase solubility in water.

In summary, while N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide exhibits good solubility in polar solvents, the specific solubility can significantly vary based on the solvent, pH, temperature, and molecular interactions. Understanding these factors can aid in optimizing the use of this compound in various applications.

Interesting facts

Interesting Facts about N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide

N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide is a fascinating compound that offers intriguing insights into the realms of medicinal chemistry and drug design. Here are some notable aspects:

  • Origin: This compound is classified as a sulfonamide, which is a well-known structural class used in various pharmaceuticals, particularly in antibiotics and antidiabetic agents.
  • Biological Activity: One of the remarkable features of this compound is its potential biological activity. It has been studied for its efficacy in targeting specific biochemical pathways, showcasing promise in treating different conditions.
  • Morpholine Moiety: The presence of the morpholine ring contributes valuable structural properties, enhancing solubility and bioavailability. This ring structure is quite versatile in drug design.
  • Structure-Activity Relationship (SAR): Researchers are keenly interested in the SAR of this compound, which helps in understanding how modifications can influence its pharmacological properties.
  • Targeted Therapy: Compounds like N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide are at the forefront of targeted therapy strategies, focusing on delivering drugs more efficiently to specific sites in the body.

In summary, N-[4-(2-morpholin-2-ylethylsulfamoyl)phenyl]acetamide represents a critical intersection of chemistry and medicine, highlighting the relentless pursuit of developing more effective therapeutic agents. The combination of its sulfonamide framework and morpholine group opens doors for innovative research and development in pharmaceuticals.