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Gabexate mesylate

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Identification
Molecular formula
C16H27N3O5S
CAS number
104376-79-6
IUPAC name
N-[4-(2-morpholin-4-ium-2-ylethylsulfamoyl)phenyl]acetamide;chloride
State
State

At room temperature, gabexate mesylate is typically in a solid state. It is usually stored in a tightly sealed container to avoid moisture absorption, which can affect its stability and efficacy.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
289.50
Boiling point (Kelvin)
562.65
General information
Molecular weight
417.36g/mol
Molar mass
417.3570g/mol
Density
1.3700g/cm3
Appearence

Gabexate mesylate appears as a white to off-white crystalline powder. This compound may also be found in granule form and is highly soluble in water, allowing it to dissolve readily for pharmaceutical applications.

Comment on solubility

Solubility of N-[4-(2-morpholin-4-ium-2-ylethylsulfamoyl)phenyl]acetamide;chloride

The solubility of N-[4-(2-morpholin-4-ium-2-ylethylsulfamoyl)phenyl]acetamide;chloride can be characterized by several key factors:

  • Ionic Nature: Being a chloride salt, this compound is expected to exhibit good solubility in polar solvents, particularly in water.
  • Intermolecular Interactions: The presence of the morpholine ring may enhance solubility due to hydrogen bonding capabilities with solvent molecules.
  • pH Dependence: The solubility may vary significantly with pH, as the ionization state of the morpholinium group can change, influencing the overall solubility profile.
  • Temperature Influence: Generally, for ionic compounds like this one, increased temperature tends to improve solubility, but specific studies are required for confirmation.

In conclusion, while the solubility of N-[4-(2-morpholin-4-ium-2-ylethylsulfamoyl)phenyl]acetamide;chloride is anticipated to be relatively high in aqueous media, precise solubility data would depend heavily on the experimental conditions, including solvent choice and pH levels. It is essential to conduct solubility tests under varying conditions to fully understand its behavior in solution.

Interesting facts

Interesting Facts about N-[4-(2-morpholin-4-ium-2-ylethylsulfamoyl)phenyl]acetamide;chloride

N-[4-(2-morpholin-4-ium-2-ylethylsulfamoyl)phenyl]acetamide;chloride is a fascinating compound that showcases the intricate interplay between organic chemistry and pharmaceuticals. This compound, featuring a morpholine moiety, suggests potential applications in medicinal chemistry and drug development.

Key Characteristics:

  • Pharmacological Relevance: The presence of the morpholine structure often indicates an affinity for biological targets, making it a subject of interest in drug design.
  • Sulfamoyl Group: The sulfamoyl functional group imparts characteristics that can enhance the compound's biological activity, possibly influencing potency and selectivity.
  • Ionizable Nature: Being a quaternary ammonium compound, its ionized nature can affect its solubility and permeability in biological systems, impacting its distribution and efficacy.

Given its complex structure, this compound can serve as a template for exploring new drug candidates aimed at specific biological pathways. As a developing area of study, researchers are keen on delving deeper into the mechanisms of action and potential therapeutic roles of compounds like this one. The potential for novel formulations or derivatives derived from this base compound opens the door to innovative therapeutic strategies.

In conclusion, N-[4-(2-morpholin-4-ium-2-ylethylsulfamoyl)phenyl]acetamide;chloride not only demonstrates the fascinating complexity of synthetic chemistry but also highlights the continuous evolution in the field of drug discovery.

Synonyms
4'-((2-Morpholinoethyl)sulfamoyl)acetanilide hydrochloride
5084 HC
Acetanilide, 4'-((2-morpholinoethyl)sulfamoyl)-, hydrochloride
N(sup 1)-(Morpholino-2 ethyle) p-acetamido benzenesulfonamide chlorhydrate [French]
1910-30-1
N(sup 1)-(Morpholino-2 ethyle) p-acetamido benzenesulfonamide chlorhydrate