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Fentanyl

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Identification
Molecular formula
C22H28N2O
CAS number
437-38-7
IUPAC name
N-[4-(2,6-dimethyl-1-piperidyl)butyl]-2-phenoxy-2-phenyl-acetamide
State
State

Fentanyl is generally a solid at room temperature.

Melting point (Celsius)
34.50
Melting point (Kelvin)
307.70
Boiling point (Celsius)
-28.40
Boiling point (Kelvin)
244.80
General information
Molecular weight
336.47g/mol
Molar mass
336.4710g/mol
Density
1.0117g/cm3
Appearence

Fentanyl is typically found as a white to off-white powder.

Comment on solubility

Solubility of N-[4-(2,6-dimethyl-1-piperidyl)butyl]-2-phenoxy-2-phenyl-acetamide

N-[4-(2,6-dimethyl-1-piperidyl)butyl]-2-phenoxy-2-phenyl-acetamide exhibits a unique solubility profile that can be affected by several factors. Understanding the solubility of this compound is crucial for its application in various chemical processes and formulations.

Factors Affecting Solubility

  • Polarity: The compound has various functional groups that can influence its overall polarity, thus affecting solubility in polar versus non-polar solvents.
  • Temperature: Solubility may increase with temperature; therefore, heating the solvent can be a practical approach when attempting to dissolve this compound.
  • pH Levels: The solubility can vary with changes in pH, so it is essential to consider the medium's acidity or basicity.

Common Solvents

Based on similar compounds, the following solvents are typically explored for dissolving N-[4-(2,6-dimethyl-1-piperidyl)butyl]-2-phenoxy-2-phenyl-acetamide:

  • Dimethyl sulfoxide (DMSO)
  • Ethyl alcohol
  • Acetone
  • Chloroform

Conclusion

Overall, the solubility of N-[4-(2,6-dimethyl-1-piperidyl)butyl]-2-phenoxy-2-phenyl-acetamide is influenced by the interplay of various chemical factors. Thorough experimentation is recommended for optimal results, as “the right solvent makes all the difference” in achieving desired solubility.

Interesting facts

Interesting Facts about N-[4-(2,6-dimethyl-1-piperidyl)butyl]-2-phenoxy-2-phenyl-acetamide

N-[4-(2,6-dimethyl-1-piperidyl)butyl]-2-phenoxy-2-phenyl-acetamide is a fascinating compound with diverse applications, particularly in the field of medicinal chemistry. Here's what makes it intriguing:

  • Potent Pharmacological Properties: This compound is a derivative of acetamide that has shown promising activity as a drug candidate. Its design leverages the unique piperidine structure, contributing to its pharmacological efficacy.
  • Structure-Activity Relationship (SAR): Researchers often explore its *structure-activity relationship*, which is crucial in understanding how modifications to its structure affect biological activity. The presence of the piperidine group and the phenoxy moiety plays a significant role in its interaction with biological targets.
  • Neurological Implications: Due to its piperidyl component, this compound has been studied for its potential effects on the nervous system. The modification of the piperidine ring may influence its ability to cross the blood-brain barrier, making it of interest in treating various neurological disorders.
  • Customizable Synthesis: Chemists value this compound for its synthetic versatility. The routes to synthesize it can be tailored, allowing for the introduction of different substituents that might enhance its therapeutic or pharmacokinetic properties.

In conclusion, N-[4-(2,6-dimethyl-1-piperidyl)butyl]-2-phenoxy-2-phenyl-acetamide is an excellent example of how molecular design can impact medicinal properties. As scientists continue to study and tweak its structure, we can look forward to discovering even more potential applications in healthcare. As one researcher aptly noted, *“The key to innovation lies in understanding the nuances of molecular architecture.”*

Synonyms
N-[4-(2,6-dimethylpiperidin-1-yl)butyl]-2-phenoxy-2-phenylacetamide
OXFENAMIDE
CHEMBL3989880
SCHEMBL29370799
NS00121145
N-[4-(2,6-DIMETHYL-1-PIPERIDINYL)BUTYL]-2-PHENOXY-2-PHENYLACETAMIDE