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Fluorophenylacetamide

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Identification
Molecular formula
C14H12FNO
CAS number
1017705-49-5
IUPAC name
N-[4-(3-fluorophenyl)phenyl]acetamide
State
State

At room temperature, Fluorophenylacetamide is in a solid state.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
245.27g/mol
Molar mass
245.2730g/mol
Density
1.2068g/cm3
Appearence

Fluorophenylacetamide appears as a white to off-white crystalline solid. It may come in the form of fine powder or small crystals depending on the purification process used during its synthesis.

Comment on solubility

Solubility Overview of N-[4-(3-fluorophenyl)phenyl]acetamide

N-[4-(3-fluorophenyl)phenyl]acetamide is a complex compound with unique solubility characteristics. Understanding its solubility can be crucial for applications in various fields, particularly in pharmaceuticals and material science.

Key Aspects of Solubility:

  • Polar vs. Nonpolar: The presence of the acetamide group typically suggests some degree of polarity, which can influence solubility in polar solvents like water.
  • Solvent Dependence: This compound may exhibit higher solubility in organic solvents such as methanol or dimethyl sulfoxide (DMSO), while being less soluble in nonpolar solvents.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature; hence, higher temperatures generally promote dissolution.
  • Influence of Substituents: The 3-fluorophenyl group can impact solubility by affecting molecular interactions, leading to variations in solubility based on structural modifications.

In conclusion, the solubility of N-[4-(3-fluorophenyl)phenyl]acetamide is influenced by several factors, including solvent choice, temperature, and molecular structure. Assessing these properties is essential for optimizing its use in various applications.

Interesting facts

Interesting Facts about N-[4-(3-fluorophenyl)phenyl]acetamide

As a compound in the realm of medicinal chemistry, N-[4-(3-fluorophenyl)phenyl]acetamide has garnered attention due to its significant biological activity and potential therapeutic applications. Here are some fascinating insights:

  • Pharmacological Potential: This compound belongs to a class known as acetamides, which are often studied for their analgesic and anti-inflammatory properties. Researchers are continually exploring its utility in developing new pain relief medications.
  • Fluorine's Role: The presence of fluorine in the structure enhances the lipophilicity of the molecule. This modification can improve the pharmacokinetic properties, such as absorption and distribution in biological systems, making it a candidate for further studies.
  • Chemical Stability: Compounds with fluorinated phenyl groups are typically more resistant to metabolic degradation. This stability can result in a longer therapeutic effect, which is crucial in drug design.
  • Diverse Applications: Beyond its potential as a pharmaceutical agent, N-[4-(3-fluorophenyl)phenyl]acetamide may also serve as a building block in the synthesis of more complex chemical entities for diverse applications in organic synthesis.
  • Research and Development: Ongoing studies may focus on understanding its mechanism of action at the molecular level. Understanding how it interacts with biological systems can unveil new pathways for targeted therapies.

In summary, N-[4-(3-fluorophenyl)phenyl]acetamide is more than just a compound; it represents a gateway into the exploration of therapeutic advancements, showcasing the intricate relationship between molecular structure and biological activity. As scientists dive deeper into its properties, the potential for innovation in drug discovery continues to expand.

Synonyms
725-06-4
ACETANILIDE, 4'-(m-FLUOROPHENYL)-
4'-(m-Fluorophenyl)acetanilide
3'-Fluoro-4-acetylaminobiphenyl
Acetamide,N-(3'-fluoro[1,1'-biphenyl]-4-yl)-
SCHEMBL17316953
DTXSID40222805