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Phenylpyrazole acetamide

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Identification
Molecular formula
C24H19N3O2
CAS number
.null
IUPAC name
N-[4-[(3-oxo-2,5-diphenyl-1H-pyrazol-4-yl)methyleneamino]phenyl]acetamide
State
State

At room temperature, N-[4-[(3-oxo-2,5-diphenyl-1H-pyrazol-4-yl)methyleneamino]phenyl]acetamide is typically a solid. It exhibits good stability under normal conditions, and its crystalline form makes it easy to handle and use in various chemical applications.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
565.00
Boiling point (Kelvin)
838.15
General information
Molecular weight
358.43g/mol
Molar mass
358.4020g/mol
Density
1.3213g/cm3
Appearence

This compound is typically presented as a crystalline solid with a yellowish-brown color. The solid form is often used in analytical and organic synthesis. The aromatic rings contribute to a slight odor characteristic of organic aromatic compounds.

Comment on solubility

Solubility of N-[4-[(3-oxo-2,5-diphenyl-1H-pyrazol-4-yl)methyleneamino]phenyl]acetamide

The solubility of N-[4-[(3-oxo-2,5-diphenyl-1H-pyrazol-4-yl)methyleneamino]phenyl]acetamide is influenced by various factors, making it a compound of interest in the realm of organic chemistry.

Key Factors Affecting Solubility:

  • Polarity: The compound contains both polar and non-polar functional groups which can lead to inconsistent solubility across different solvents.
  • Solvent Choice: Typically, it may show better solubility in slightly polar solvents such as ethanol or methanol, than in non-polar solvents.
  • Temperature: An increase in temperature may enhance solubility, as kinetic energy allows for better interaction between the solvent and solute molecules.

As with many organic compounds, solubility is context-dependent. It is often said that "like dissolves like," meaning that polar molecules tend to dissolve well in polar solvents, while non-polar molecules do better in non-polar solvents. Therefore, the key to maximizing solubility for N-[4-[(3-oxo-2,5-diphenyl-1H-pyrazol-4-yl)methyleneamino]phenyl]acetamide lies in carefully selecting the appropriate solvent system based on its molecular characteristics.

Furthermore, the presence of functional groups, such as amides and aromatic rings, can influence hydrogen bonding interactions, further complicating solubility behavior. This highlights the necessity of conducting systematic solubility tests under controlled conditions to fully ascertain the behavior of this compound in various environments.

Interesting facts

Interesting Facts about N-[4-[(3-oxo-2,5-diphenyl-1H-pyrazol-4-yl)methyleneamino]phenyl]acetamide

N-[4-[(3-oxo-2,5-diphenyl-1H-pyrazol-4-yl)methyleneamino]phenyl]acetamide is a fascinating compound known for its diverse applications in the field of medicinal chemistry. Here are some intriguing facts about this remarkable molecule:

  • Pharmacological Potential: The compound exhibits significant biological activity, making it a candidate for developing various pharmaceuticals. Its structure suggests potential effects as an anti-inflammatory or analgesic agent.
  • Structural Diversity: The presence of the pyrazole ring in its molecular framework contributes to the compound's unique properties. This feature is often associated with various biological activities, including antitumor and antibacterial effects.
  • Mechanistic Insights: Researchers are particularly interested in understanding how this compound interacts at the molecular level, as it may inhibit specific pathways involved in disease progression.
  • Importance in Synthesis: This compound can serve as an intermediate in organic synthesis, making it a valuable building block in creating more complex molecules.
  • Research Spotlight: Several studies have been published examining the efficacy and safety of this compound, indicating its potential role as a template for future drug development.

Overall, N-[4-[(3-oxo-2,5-diphenyl-1H-pyrazol-4-yl)methyleneamino]phenyl]acetamide represents a key subject of interest for chemists aiming to explore innovative solutions to health challenges. As the field of medicinal chemistry continues to evolve, compounds like this one pave the way for exciting discoveries and advancements.

Synonyms
24664-64-0
BRN 0853635
4'-((1,3-Diphenyl-5-oxo-2-pyrazolin-4-ylidene)methylamino)acetanilide
ACETANILIDE, 4'-((1,3-DIPHENYL-5-OXO-2-PYRAZOLIN-4-YLIDENE)METHYLAMINO)-
4'-[[(1,3-Diphenyl-5-oxo-2-pyrazolin-4-ylidene)methyl]amino]acetanilide