Skip to main content

Sulfentrazone

ADVERTISEMENT
Identification
Molecular formula
C11H10F6N4O2S
CAS number
122836-35-5
IUPAC name
N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-thiadiazole-5-carboxamide
State
State
This compound is in a solid state at room temperature, characterized as a powder.
Melting point (Celsius)
123.50
Melting point (Kelvin)
396.65
Boiling point (Celsius)
336.60
Boiling point (Kelvin)
609.75
General information
Molecular weight
387.37g/mol
Molar mass
387.3590g/mol
Density
1.6350g/cm3
Appearence

Sulfentrazone is a white crystalline substance that is mostly used in its solid form. It appears as a fine, off-white powder under standard conditions.

Comment on solubility

Solubility of N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-thiadiazole-5-carboxamide

N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-thiadiazole-5-carboxamide, with the chemical formula C11H10F6N4O2S, exhibits unique solubility properties that can be influenced by a variety of factors. When discussing the solubility of this compound, several key points should be considered:

  • Polarity: The presence of electronegative fluorine atoms contributes to the compound's overall polarity, which may affect its solubility in polar solvents such as water.
  • Hydrophobic Interactions: The hydrophobic nature of the thiadiazole and pyrazole rings may impede solubility in highly polar solvents, making it more soluble in organic solvents like DMSO or ethanol.
  • Functional Groups: The carboxamide group can interact with water molecules via hydrogen bonding, potentially enhancing solubility in certain conditions.
  • Temperature Dependence: Solubility is often temperature-dependent, and increasing the temperature may lead to greater solubility in various solvents.
  • Concentration Effects: Precise solubility levels can vary depending on concentration and the presence of other solutes.

It is essential to note that while some experimental conditions might lead to satisfactory solubility, others may not yield the same results. As a result, understanding the specific context in which this compound is being used can provide additional insights into its solubility behavior.

Interesting facts

Interesting Facts about N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-thiadiazole-5-carboxamide

This compound is a fascinating example of a synthetic organic molecule that demonstrates the intricate relationship between structure and function in chemistry. As a scientist or chemistry student, you might find the following aspects particularly intriguing:

  • Fluorinated Features: The presence of trifluoromethyl groups significantly enhances the biological activity of compounds. Fluorine atoms can affect both the lipophilicity and reactivity of the molecule, making it a common modification in medicinal chemistry.
  • Dual Heterocyclic Framework: N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-thiadiazole-5-carboxamide incorporates two heterocyclic systems: a pyrazole and a thiadiazole. This combination can lead to unique interactions in biological systems, potentially influencing pharmacological properties.
  • Potential Biological Applications: Compounds with similar structures have been studied for their roles as anti-inflammatory agents, antiparasitic, and anticancer drugs. Investigating similar molecules can pave the way for developing novel therapeutics.
  • Synthesis Challenges: The synthesis of this compound may involve multi-step reactions, which can be a thrilling investigative process. Each synthetic step provides valuable learning outcomes concerning reaction mechanisms and yields.

As you delve deeper into your studies, remember the words of Linus Pauling: "The best way to have a good idea is to have a lot of ideas." This compound exemplifies how creativity in structural design can lead to new discoveries in the world of chemistry.

Exploration and innovation in the field of chemical compounds like N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-thiadiazole-5-carboxamide exemplify the continuous quest for knowledge and advancement in pharmaceuticals and materials science.

Synonyms
223499-30-7
btp2
YM-58483
CRAC Channel Inhibitor, BTP2
N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
N-(4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide
N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide
CHEMBL262766
YM 58483
4-methyl-4'-(3,5-bis(trifluoromethyl)-1h-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide
4-methyl-4'-[3,5-bis(trifluoromethyl)-1h-pyrazol-1-yl]-1,2,3-thiadiazole-5-carboxanilide
n-{4-[3,5-bis(trifluoromethyl)-1h-pyrazol-1-yl]phenyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide
BTP2 cpd
BTP-2
MFCD00220976
YM-58483 (BTP2)
Maybridge3_006679
SCHEMBL676045
GTPL2438
DTXSID50274370
XPRZIORDEVHURQ-UHFFFAOYSA-N
HMS1449P13
HMS3648I22
HMS3886H10
YM-58483 (BTP2 pound(c)
BCP19298
EX-A2467
BDBM50204544
CCG-55182
s8380
AKOS024457886
CS-6047
YM58483
IDI1_018066
NCGC00344111-03
AC-35791
AS-16763
DB-221563
HY-100831
YM-58483?
C74150
YM-58483, >=98% (HPLC)
SR-01000644222
SR-01000644222-1
SR-01000644222-3
BRD-K42563464-001-01-9
Q27075544
CRAC Channel Inhibitor, BTP2 - CAS 223499-30-7
4-Methyl-[1,2,3]thiadiazole-5-carboxylic acid [4-(3,5-bis-trifluoromethyl-pyrazol-1-yl)-phenyl]-amide
636-569-2
n-{4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide