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Acetaminophen

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Identification
Molecular formula
C8H9NO2
CAS number
103-90-2
IUPAC name
N-[4-[4-[3-(dimethylamino)propyl]piperazin-1-yl]phenyl]acetamide
State
State

Acetaminophen is typically found in a solid state at room temperature.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.00
Boiling point (Celsius)
409.00
Boiling point (Kelvin)
682.00
General information
Molecular weight
165.19g/mol
Molar mass
165.1900g/mol
Density
1.2000g/cm3
Appearence

Acetaminophen is typically a white, crystalline powder. It is odorless and has a slightly bitter taste. It is commonly used in medicine and pharmaceuticals, particularly in tablets and liquid suspension forms.

Comment on solubility

Solubility of N-[4-[4-[3-(dimethylamino)propyl]piperazin-1-yl]phenyl]acetamide

The solubility of N-[4-[4-[3-(dimethylamino)propyl]piperazin-1-yl]phenyl]acetamide is an intriguing topic due to its complex structure and potential implications in various chemical and biological applications.

Generally, the solubility of this compound can be influenced by several key factors:

  • Polarity: The presence of the dimethylamino group increases the polarity of the molecule, which may enhance its solubility in polar solvents, such as water.
  • Hydrogen Bonding: The acetamide functionality can engage in hydrogen bonding, making it more soluble in solvents that can either donate or accept hydrogen bonds.
  • Alkyl Chains: The dimethylamino and propyl groups introduce hydrophobic characteristics, which may affect solubility in non-polar solvents.
  • pH Dependency: Solubility may vary with pH due to the potential ionization of the dimethylamino group, which could enhance solubility in basic conditions.

In summary, the solubility of N-[4-[4-[3-(dimethylamino)propyl]piperazin-1-yl]phenyl]acetamide is likely to present unique behaviors based on its structural properties. As one researcher noted, “Understanding molecular interactions is key to predicting solubility.” Therefore, exploring different solvent systems can yield valuable insights into the solubility profile of this compound.

Interesting facts

Interesting Facts about N-[4-[4-[3-(dimethylamino)propyl]piperazin-1-yl]phenyl]acetamide

N-[4-[4-[3-(dimethylamino)propyl]piperazin-1-yl]phenyl]acetamide is a fascinating compound that showcases the complexity and versatility of organic chemistry. Here are some intriguing aspects of this compound:

  • Pharmaceutical Relevance: This compound is often investigated for its potential use in pharmacology. Its structure suggests it may have interactions with certain neurotransmitter receptors, making it a candidate for studies in mental health treatments.
  • Structural Complexity: The presence of a piperazine ring coupled with a dimethylamino group adds layers of complexity to its properties. These functional groups are known for their role in enhancing bioactivity and solubility.
  • Potential Applications: Compounds like this one are often studied for applications in drug design, particularly in the development of agents for the treatment of conditions such as anxiety, depression, or schizophrenia.
  • Research Interest: The design and synthesis of similar compounds is a hot topic in medicinal chemistry, where researchers explore modifications to improve selectivity and reduce side effects.

The ever-evolving field of chemistry continually opens new avenues for exploration with compounds like N-[4-[4-[3-(dimethylamino)propyl]piperazin-1-yl]phenyl]acetamide, as scientists strive to understand and utilize the interactions that define their biological potency.

In the words of renowned chemist Linus Pauling: "Chemistry is the study of symmetry." The intricate design of this compound exemplifies the beautiful symmetry inherent in molecular architecture.

Synonyms
PIPERAMIDE
Piperamide [INN]
299-48-9
UNII-83B7UZO20C
piperamida
83B7UZO20C
4'-(4-(3-(DIMETHYLAMINO)PROPYL)-1-PIPERAZINYL)ACETANILIDE
ACETAMIDE, N-(4-(4-(3-(DIMETHYLAMINO)PROPYL)-1-PIPERAZINYL)PHENYL)-
piperamidum
N-[4-[4-[3-(dimethylamino)propyl]piperazin-1-yl]phenyl]acetamide
SCHEMBL635749
CHEMBL1945318
DTXSID10952349
Q27269425
N-(4-{4-[3-(Dimethylamino)propyl]piperazin-1-yl}phenyl)ethanimidic acid