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Paracetamol

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Identification
Molecular formula
C8H9NO2
CAS number
103-90-2
IUPAC name
N-[4-(4-acetamido-2-methyl-phenyl)-3-methyl-phenyl]acetamide
State
State

At room temperature, paracetamol is typically in a solid state. It is stable under normal conditions of temperature and pressure, and it is commonly found in tablet or powdered form for pharmaceutical use.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
151.16g/mol
Molar mass
151.1630g/mol
Density
1.2630g/cm3
Appearence

Paracetamol is a white, crystalline substance. It can be seen in powder or granule form and is generally odorless and tasteless. It is often used in its solid tablet form for medicinal purposes.

Comment on solubility

Solubility of N-[4-(4-acetamido-2-methyl-phenyl)-3-methyl-phenyl]acetamide

This compound, known as N-[4-(4-acetamido-2-methyl-phenyl)-3-methyl-phenyl]acetamide, exhibits variable solubility characteristics that can be influenced by several factors. Understanding its solubility behavior is crucial for its applications in various fields, especially in pharmaceuticals and organic synthesis.

Solubility in Common Solvents

The solubility of N-[4-(4-acetamido-2-methyl-phenyl)-3-methyl-phenyl]acetamide can be summarized as follows:

  • Water: This compound is typically insoluble or has very low solubility in water due to its hydrophobic aromatic rings.
  • Organic Solvents: It shows enhanced solubility in common organic solvents such as:
    • Ethanol
    • Dimethyl Sulfoxide (DMSO)
    • Acetone

Factors Affecting Solubility

Several factors can affect the solubility of this compound:

  • Temperature: As with many organic compounds, an increase in temperature typically leads to an increase in solubility.
  • pH: The presence of various ionic species in solution can alter the solubility by affecting the ionization state of the molecule.
  • Presence of Co-solvents: Blending with other solvents can improve solubility, often leading to better dissolution properties.

In conclusion, while N-[4-(4-acetamido-2-methyl-phenyl)-3-methyl-phenyl]acetamide has specific solubility traits concerning polar and nonpolar environments, it is essential to consider the listed factors when aiming to dissolve this compound for practical applications. Understanding these attributes allows chemists to predict behavior and optimize formulations effectively.

Interesting facts

Interesting Facts about N-[4-(4-acetamido-2-methyl-phenyl)-3-methyl-phenyl]acetamide

N-[4-(4-acetamido-2-methyl-phenyl)-3-methyl-phenyl]acetamide, commonly known in scientific literature, is a compound that showcases intriguing characteristics and potential applications in various fields.

Chemical Significance

  • Pharmaceutical Role: This compound, due to its amide functional group, can exhibit significant biological activity, potentially serving as a lead compound in drug design and development.
  • Structural Complexity: The intricate structure of this molecule indicates a highly substituted aromatic system, often associated with enhanced properties such as solubility and stability.

Potential Applications

  • Medicinal Applications: Compounds with amide linkages are frequently found in various therapeutic agents. They could be studied for their potential anti-inflammatory or analgesic activities.
  • Chemical Research: This compound can serve as a useful intermediate in organic synthesis, offering a pathway for constructing more complex molecules.

Unique Characteristics

This compound illustrates the interaction of multiple functional groups, making it a candidate for studies in structure-activity relationships (SAR). As stated in research, "The diverse functionalities can provide insights into the biochemical pathways affected by such compounds." By exploring the biological effects associated with these modifications, researchers can enhance our understanding of medicinal chemistry and its applications.

Conclusion

In summary, N-[4-(4-acetamido-2-methyl-phenyl)-3-methyl-phenyl]acetamide is a notable compound in chemical research with promising prospects in pharmaceuticals and organic synthesis. Its unique structural features and potential bioactivity make it a focal point for ongoing studies in the field of chemistry.

Synonyms
3,3'-Dimethyl-N,N'-diacetylbenzidine
3546-11-0
BRN 3379784
3',3'''-Dimethyl-4',4'''-biacetanilide
4-13-00-00420 (Beilstein Handbook Reference)
4',4'''-BIACETANILIDE, 3',3'''-DIMETHYL-
N-[4-(4-acetamido-2-methylphenyl)-3-methylphenyl]acetamide
Oprea1_780906
N-[4'-(acetylamino)-2,2'-dimethyl[1,1'-biphenyl]-4-yl]acetamide
AKOS024275105