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Paracetamol

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Identification
Molecular formula
C8H9NO2
CAS number
103-90-2
IUPAC name
N-[4-(4-aminophenyl)phenyl]acetamide
State
State

Paracetamol is typically found in a solid state at room temperature.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
151.16g/mol
Molar mass
151.1630g/mol
Density
1.2630g/cm3
Appearence

Paracetamol, commonly known as acetaminophen, appears as a white, crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of N-[4-(4-aminophenyl)phenyl]acetamide

N-[4-(4-aminophenyl)phenyl]acetamide, a compound often encountered in pharmaceutical and chemical research, exhibits unique solubility characteristics. The solubility of this compound can be influenced by various factors, including:

  • Temperature: Solubility often increases with temperature; hence, higher temperatures may enhance the dissolution of N-[4-(4-aminophenyl)phenyl]acetamide in solvents.
  • pH Level: As with many amide compounds, a change in pH can impact the solubility, with different ionization states leading to varied solubility profiles.
  • Solvent Choice: The compound demonstrates varying solubility in different solvents. It is primarily soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), while its solubility in water is generally low due to its hydrophobic characteristics.

Understanding the solubility of N-[4-(4-aminophenyl)phenyl]acetamide is crucial for its applications, particularly in drug formulation, where solubility plays a key role in bioavailability. As with many organic compounds, predicting solubility can often be complex, but the interplay of the above factors provides a framework for understanding its behavior in different environments.

Interesting facts

Interesting Facts about N-[4-(4-aminophenyl)phenyl]acetamide

N-[4-(4-aminophenyl)phenyl]acetamide, also known as a derivative of acetamide, is a compound that presents intriguing aspects for both researchers and students in the field of chemistry. It is defined by its unique structure and various potential applications:

  • Pharmaceutical Relevance: This compound is of interest in medicinal chemistry due to its potential activity in drug development. Its ability to interact with biological targets makes it a candidate for further pharmaceutical research.
  • Structural Characteristics: The presence of amino and acetamide functional groups in the molecule contributes to its reactivity and ability to form hydrogen bonds, making it an interesting subject of study in organic synthesis.
  • Applications in Material Science: Compounds with similar structures have been studied for use in organic electronics and as materials in various technological applications, showcasing the versatility of this type of compound.
  • Research Opportunities: The synthesis of N-[4-(4-aminophenyl)phenyl]acetamide offers an excellent opportunity for students to learn about reaction mechanisms and purification processes, enhancing their practical laboratory skills.

Moreover, the exploration of this compound serves as a gateway into understanding the broader implications of amide functionality in organic chemistry. As quoted in many texts, “Understanding the molecular structure is key to unlocking the potential of chemical compounds.” Thus, N-[4-(4-aminophenyl)phenyl]acetamide stands as a promising compound worthy of exploration in both academic and industrial settings. Its unique properties and applications highlight the importance of structure-activity relationship studies in developing new materials and pharmaceuticals.

Synonyms
N-Acetylbenzidine
3366-61-8
Monoacetylbenzidine
N-Acetylbenzidin
4'-Acetamidobenzidine
Benzidine, N-acetyl-
4-Acetamido-4'-aminobiphenyl
4-Acetylamino-4'-aminobiphenyl
ACETANILIDE, 4'-(p-AMINOPHENYL)-
acetylbenzidine
4'-(p-Aminophenyl)acetanilide
CCRIS 5166
(1,1'-Biphenyl)-4,4'-diamine, N-acetyl-
Acetamide, N-(4'-amino(1,1'-biphenyl)-4-yl)-
UNII-Q1I4IM38KC
Q1I4IM38KC
NSC 508901
BRN 2806506
NSC-508901
Acetamide, N-(4'-amino[1,1'-biphenyl]-4-yl)-
DTXSID4036853
3-13-00-00437 (Beilstein Handbook Reference)
ACETANILIDE, P-(P-AMINOPHENYL)-
N-Acetylbenzidin [Czech]
DTXCID2016853
Acetamide, N-(4'-amino(1,1'-biphenyl)-4-yl)-(9CI)
N-[4-(4-aminophenyl)phenyl]acetamide
N-(4'-Amino-[1,1'-biphenyl]-4-yl)acetamide
N-(4'-Aminobiphenyl-4-yl)acetamide
N-{4'-amino-[1,1'-biphenyl]-4-yl}acetamide
N-Acetylbenzidin [Czech]
MFCD00047857
N-(4'-Amino-biphenyl-4-yl)-acetamide
WLN: ZR DR DMV1
Oprea1_125494
[1,4'-diamine, N-acetyl-
SCHEMBL3225408
ALBB-031702
NSC508901
AKOS002813326
SB79759
LS-11528
CS-0320333
NS00115907
Q26840965