Interesting facts
Interesting Facts About N-[4-(4-formamidophenyl)sulfonylphenyl]formamide
N-[4-(4-formamidophenyl)sulfonylphenyl]formamide is a fascinating compound that draws attention due to its unique structure and potential applications. Here are some interesting aspects that highlight its significance:
- Versatile Applications: This compound is a critical intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. Its reactivity allows for various transformations, making it valuable in drug design.
- Biological Activity: Compounds containing sulfonamide groups, like N-[4-(4-formamidophenyl)sulfonylphenyl]formamide, often exhibit antimicrobial properties. This raises interest in exploring its potential as a therapeutic agent.
- Synthetic Pathways: The synthesis of this compound can involve multiple steps including the formation of sulfonamide linkages and the introduction of formyl groups. Understanding these pathways is essential for chemists aiming to optimize yield or purity.
- Structure-Activity Relationship (SAR): Researching the SAR of compounds like this one can yield insights into how structural modifications affect biological efficacy. This information is crucial for medicinal chemistry and rational drug design.
- Intermolecular Interactions: The presence of both sulfonamide and formamide functionalities suggests interesting hydrogen-bonding interactions, which can influence solubility and reactivity in different solvents.
- Research and Development: Ongoing studies often focus on enhancing the properties of this compound to develop more potent and selective agents for diverse antibacterial or antitumor activity.
In addition to its scientific relevance, N-[4-(4-formamidophenyl)sulfonylphenyl]formamide serves as a reminder of the intricate connections between chemical structure and function. As researchers continue to explore and expand the applications of this and similar compounds, the importance of interdisciplinary approaches in chemistry becomes increasingly clear.
Synonyms
Diformyldapsone
Diformyl dapsone
Formilone
6784-25-4
Diformyl diaminodiphenylsulfone
DFDDS
Diformyl-4,4'-sulfonyldianiline
4,4'-Diformamidodiphenyl sulfone
p,p'-Sulfonylbisformanilide
WR 6798
N-[4-(4-formamidophenyl)sulfonylphenyl]formamide
Sulfone, bis(N-formyl-p-aminophenyl)
Formamide, N,N'-(sulfonyldi-4,1-phenylene)bis-
NSC53674
TF8F6OBI8Q
4,4'-diformamidodiphenylsulfone
DFD
NSC-53674
WR-6798
Formanilide, 4',4'''-sulfonyldi-
NSC 53674
Formanilide, 4',4'''-sulfonylbis-
BRN 2815334
N,N'-Diformyl-p,p'-diaminodiphenylsulfone
UNII-TF8F6OBI8Q
Diformamido diphenylsulfone
N,p'-diaminodiphenylsulfone
4,4'-sulfonylbisformanilide
WLN: VHMR DSWR DMVH
3-13-00-01270 (Beilstein Handbook Reference)
Formanilide,4'''-sulfonyldi-
Formanilide,4'''-sulfonylbis-
SCHEMBL3955572
CHEMBL2001327
DTXSID70218079
P,P'-SULFONYLBIS(FORMANILIDE)
FORMANILIDE, 4,4'-SULFONYLBIS-
NCI60_004323
Formamide,N'-(sulfonyldi-4,1-phenylene)bis-
N,N'-(Sulfonylbis(4,1-phenylene))diformamide
Solubility of N-[4-(4-formamidophenyl)sulfonylphenyl]formamide
N-[4-(4-formamidophenyl)sulfonylphenyl]formamide, with its complex structure, exhibits interesting solubility characteristics that warrant attention. This compound is generally soluble in polar solvents due to the presence of functional groups that can engage in hydrogen bonding. Below are some key points regarding its solubility:
In contrast, this compound is expected to be insoluble or only slightly soluble in non-polar solvents like hexane or benzene, owing to the lack of favorable interactions with these types of solvents.
Consequently, its solubility profile reflects its molecular design, which combines hydrophilic and hydrophobic elements. As always, practical experimentation will provide definitive insights into conformation and behavior in various media.