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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4S
CAS number
59-87-0
IUPAC name
N-[4-(5-nitro-2-furyl)thiazol-2-yl]acetamide
State
State

Nitrofurazone exists as a solid at room temperature.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.00
Boiling point (Celsius)
277.00
Boiling point (Kelvin)
550.00
General information
Molecular weight
198.20g/mol
Molar mass
198.1560g/mol
Density
1.6700g/cm3
Appearence

Nitrofurazone typically appears as a yellow crystalline powder. It may dissolve in warm water but is noted for its vivid coloration, which is characteristic of nitroaromatic compounds.

Comment on solubility

Solubility of N-[4-(5-nitro-2-furyl)thiazol-2-yl]acetamide

The solubility of N-[4-(5-nitro-2-furyl)thiazol-2-yl]acetamide can vary significantly based on environmental conditions, particularly temperature and pH of the solvent. This compound displays characteristics typical of its class, suggesting a moderate solubility profile in polar solvents.

  • Water Solubility: This compound may exhibit limited solubility in water due to its aromatic and heterocyclic structure.
  • Organic Solvents: It is likely to be more soluble in organic solvents, such as methanol or ethanol, which can assist in dissolving structurally complex organic compounds.
  • pH Dependence: The solubility may improve or decline based on changes in pH, particularly if the compound possesses functional groups that can ionize.

In general, **polar solvents** enhance solubility for compounds like N-[4-(5-nitro-2-furyl)thiazol-2-yl]acetamide, while **non-polar solvents** may provide less favorable conditions for dissolution. Therefore, understanding the solubility characteristics of this compound is crucial for applications in pharmaceuticals and chemical research.

Interesting facts

Interesting Facts about N-[4-(5-nitro-2-furyl)thiazol-2-yl]acetamide

N-[4-(5-nitro-2-furyl)thiazol-2-yl]acetamide is a fascinating compound due to its unique structure and potential applications. This chemical belongs to the class of **thiazole derivatives**, which are known for their diverse biological activities.

Key Characteristics

  • Biological Activity: Thiazole-containing compounds often exhibit a range of biological activities, such as antimicrobial, antifungal, and anticancer properties. This makes them a topic of interest in medicinal chemistry.
  • Structure-Activity Relationship: The presence of a nitro group and furyl ring in the structure of N-[4-(5-nitro-2-furyl)thiazol-2-yl]acetamide can significantly influence its reactivity and biological efficacy.
  • Synthetic Pathways: The synthesis of thiazole derivatives can involve various methods, including cyclization reactions and functional group transformations, which are pivotal in expanding the library of bioactive compounds.

Potential Applications

This compound is not only of academic interest but also holds potential for various applications:

  • Development of pharmaceuticals targeting specific diseases.
  • Use in agricultural chemistry as potential pesticides due to its biological activities.
  • Investigation in the field of material science for possible applications in organic electronics.

Quote to Consider

As Albert Einstein once said, "If you can't explain it simply, you don't understand it well enough." Understanding complex compounds like N-[4-(5-nitro-2-furyl)thiazol-2-yl]acetamide can lead to breakthroughs in many fields.

The exploration of compounds like this one is crucial for advancements in science and technology, reminding us of the intricate connections between chemistry and the wider world.

Synonyms
Furothiazole
Furathiazole
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
N-(4-(5-Nitro-2-furyl)-2-thiazolyl)acetamide
CCRIS 446
2-Acetylamino-4-(5-nitro-2-furyl)thiazole
UNII-Q42HOE346S
AS17665
BACTOFURIL
BRN 0544226
Q42HOE346S
2-Acetamino-4-(5-nitro-2-furyl)thiazole
Thiazole, 2-acetamido-4-(5-nitro-2-furyl)-
Thiazole, 2-acetamino-4-(5-nitro-2-furyl)-
Thiazole, 2-acetylamino-4-(5-nitro-2-furyl)-
N-(4-(5-NITRO-2-FURANYL)-2-THIAZOLYL)ACETAMIDE
DTXSID9020952
Acetamide, N-(4-(5-nitro-2-furanyl)-2-thiazolyl)-
Acetamide, N-[4-(5-nitro-2-furanyl)-2-thiazolyl]-
N-(4-(5-NITRO-2-FURYL)-2-THIAZOLYL)ACETAMIDE [IARC]
N-[4-(5-nitro-2-furanyl)-2-thiazolyl]acetamide
N-(4-(5-NITRO-2-FURYL)-2-THIAZOLYL)ACETAMIDE (IARC)
DTXCID50952
531-82-8
NFTA
Furium
N-[4-(5-nitrofuran-2-yl)-1,3-thiazol-2-yl]acetamide
2-Acetamido-4-(5-nitro-2-furyl)thiazole
CHEBI:82353
N-(4-(5-nitrofuran-2-yl)thiazol-2-yl)acetamide
Acetamide, N-(4-(5-nitro-2-furyl)-2-thiazolyl)-
CHEMBL259186
SCHEMBL3824030
GYRMPDLIHUXUIG-UHFFFAOYSA-N
DB-172924
C19273
Q27155894