Skip to main content

Nitrofurazone

ADVERTISEMENT
Identification
Molecular formula
C6H6N4O4S
CAS number
59-87-0
IUPAC name
N-[4-(5-nitro-2-furyl)thiazol-2-yl]formamide
State
State

At room temperature, nitrofurazone is a solid. Its bright yellow crystalline powder form is stable under standard conditions.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.00
Boiling point (Celsius)
465.00
Boiling point (Kelvin)
738.00
General information
Molecular weight
198.16g/mol
Molar mass
198.1560g/mol
Density
1.6605g/cm3
Appearence

Nitrofurazone appears as a bright yellow powder. It is crystalline in nature, and this vibrant yellow coloration is a characteristic feature due to the presence of nitro compounds.

Comment on solubility

Solubility of N-[4-(5-nitro-2-furyl)thiazol-2-yl]formamide

The solubility of N-[4-(5-nitro-2-furyl)thiazol-2-yl]formamide is a topic of interest due to its unique chemical structure and properties. Understanding its solubility can shed light on its potential applications in various fields.

  • Solvent Interaction: This compound may exhibit solubility in polar solvents such as water and ethanol, owing to the presence of functional groups that can engage in hydrogen bonding.
  • pH Dependency: The solubility may vary with pH, particularly if the formamide group undergoes protonation under acidic conditions, enhancing its solubility.
  • Temperature Effects: Generally, an increase in temperature can lead to increased solubility of organic compounds. Therefore, warming the solution might be beneficial.
  • Crystallization: Given its complexity, careful control of crystallization conditions is necessary, as rapid cooling may lead to less soluble crystalline forms.

It’s crucial to observe that the phenyl-nitro and thiazole moieties may also influence solubility, potentially making it less soluble in non-polar solvents due to their hydrophobic nature.

In conclusion, while N-[4-(5-nitro-2-furyl)thiazol-2-yl]formamide may have good solubility in certain conditions, factors such as solvent choice, temperature, and pH levels play a significant role in determining its solubility profile.

Interesting facts

Interesting Facts about N-[4-(5-nitro-2-furyl)thiazol-2-yl]formamide

N-[4-(5-nitro-2-furyl)thiazol-2-yl]formamide is a fascinating compound within the realm of organic chemistry, particularly noted for its potential applications in medicinal chemistry and agrochemicals. Here are some intriguing points about this compound:

  • Unique Structure: The compound features a thiazole ring and a nitro group attached to a furan, providing a diverse framework that enhances its biological activity.
  • Biological Activity: Similar compounds have been studied for their efficacy against various biological targets, including potential anti-cancer properties and antibacterial effects. The electron-withdrawing nitro group can significantly impact its reactivity and interactions.
  • Versatile Use: Due to its structural characteristics, this compound could serve as a key intermediate in the synthesis of more complex molecules, contributing to the development of new pharmaceuticals.
  • Mechanism of Action: Compounds like this one that contain thiazole and nitro functionalities may exhibit unique mechanisms of action, potentially interacting with enzymes or binding to DNA, making them subjects of ongoing research.
  • Environmental Impact: As with many chemical compounds, understanding the environmental persistence and toxicity of this compound encourages researchers to explore more sustainable and less harmful alternatives in agricultural practices.

In conclusion, N-[4-(5-nitro-2-furyl)thiazol-2-yl]formamide represents an important compound worth investigating further. Its rich structural features and possible applications make it an exciting topic for research and exploration in the chemical sciences.

Synonyms
FANFT
24554-26-5
N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]formamide
2-Formylamino-4-(5-nitro-2-furyl)thiazole
7N99PZG62O
DTXSID4020953
Formamide, N-(4-(5-nitro-2-furanyl)-2-thiazolyl)-
NSC-155010
Formamide, N-(4-(5-nitro-2-furyl)-2-thiazolyl)-
Formamide, N-[4-(5-nitro-2-furanyl)-2-thiazolyl]-
Formamide, N-[4-(5-nitro-2-furyl)-2-thiazolyl]-
RefChem:139928
N-4-(5-Nitro-2-furyl)-2-thiazolylformamide
DTXCID80953
N-[4-(5-nitrofuran-2-yl)-1,3-thiazol-2-yl]formamide
NSC 155010
N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamid
N-(4-(5-nitrofuran-2-yl)thiazol-2-yl)formamide
N-((4-(5-Nitro-2-furyl)-2-tiazolyl))formamide
CCRIS 308
N-[(4-(5-Nitro-2-furyl)-2-tiazolyl)]formamide
UNII-7N99PZG62O
Formamide,N-[4-(5-nitro-2-furanyl)-2-thiazolyl]-
N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamid [German]
Oprea1_795022
CHEMBL82444
SCHEMBL2592673
NSC155010
STL295943
AKOS015831837
4-(5-Nitro-2-furyl)-1,3-thiazol-2-ylformamide #
Q27268602
N-(4-(5-NITRO-2-FURANYL)-2-THIAZOLYL)FORMAMIDE