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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-(4-amino-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide
State
State
Lidocaine is usually in solid state at room temperature and is commonly available as an injectable solution or topical formulation.
Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.95
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence
Lidocaine is typically found as a colorless crystalline solid or as a white powder. It is odorless and has a slightly bitter taste.
Comment on solubility

Solubility of N-(4-amino-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide

This compound, commonly known by its complex name, exhibits interesting solubility properties that can be quite significant in various applications. Understanding its solubility behavior is paramount for practical usage in pharmaceuticals or other chemical processes. Here are some key points regarding its solubility:

  • Solvent Dependence: The solubility of N-(4-amino-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide is highly dependent on the nature of the solvent. Typically, such amides are more soluble in polar solvents.
  • Temperature Influence: Increasing the temperature often enhances the solubility of organic compounds, thus it may exhibit better solubility at elevated temperatures.
  • pH Sensitivity: Being an amine derivative, its solubility could vary significantly with pH changes. It can become more soluble in acidic conditions where protonation occurs.
  • Hydrogen Bonding: The presence of amino groups allows for potential hydrogen bonding with water molecules, which can increase the solubility in aqueous solutions.

In summary, the solubility characteristics of N-(4-amino-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide are complex and influenced by several factors including solvent polarity, temperature, and pH. As those in the field often say, “Understanding solubility is key to unlocking the potential of a compound.” This emphasizes the need for thorough investigation into solubility for effective application in various domains.

Interesting facts

Interesting Facts About N-(4-amino-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide

N-(4-amino-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide, commonly known in certain contexts for its potential therapeutic applications, showcases a fascinating blend of chemical characteristics and biological relevance. Here are some intriguing facts about this compound:

  • Pharmaceutical Relevance: This compound is often explored in drug discovery programs due to its structural features, which suggest potential efficacy in targeting various biological pathways.
  • Structural Diversity: The presence of both an amino group and a diethylamino group in its structure enhances its potential interactions within the body, making it a candidate for developing medications that require specific binding properties.
  • Research Focus: Scientists have been particularly interested in its role as an analgesic agent. Its unique design allows for diverse pharmacological studies, expanding our understanding of pain management therapies.
  • Mechanism of Action: Although ongoing research is necessary, initial studies indicate that compounds like this may influence neurotransmitter pathways, suggesting a modulation of pain and emotional responses.
  • Synthetic Pathways: The synthesis of this compound involves multi-step chemical reactions, making it an interesting subject for organic chemists aiming to develop efficient synthetic methodologies.

As a compound that merges organic chemistry with practical medical applications, N-(4-amino-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide epitomizes the complexity and potential of small organic molecules in modern pharmacology. Its journey from a simple chemical structure to a candidate for therapeutic intervention underscores the intricate connections between chemistry and medicine.

In the words of chemist Robert H. Grubbs, "The most potent tools we have are not simply new reactions but our understanding of how to merge scientific disciplines to solve complex problems." This encapsulates the essence of N-(4-amino-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide in the pursuit of innovative healthcare solutions.

Synonyms
n-(4-amino-2,6-dimethylphenyl)-n2,n2-diethylglycinamide
27951-88-8
N-(4-amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide
CHEMBL5016790
SCHEMBL11654851
DTXSID60275090
AH-034/08305041