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N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide

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Identification
Molecular formula
C14H17ClN2O2S
CAS number
56287-41-3
IUPAC name
N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide
State
State

At room temperature, N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide is a solid. It is stable under normal conditions but should be stored away from light and moisture to prevent degradation.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
330.84g/mol
Molar mass
330.8360g/mol
Density
1.3400g/cm3
Appearence

The compound N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide typically appears as a crystalline solid. The exact color might vary depending on purity and preparation, but it often appears as a white or off-white powder. It is usually odorless or may have a slight chemical odor.

Comment on solubility

Solubility of N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide

The solubility of N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide (C14H17ClN2O2S) can be quite nuanced, depending on the environmental conditions and the solvent used. Understanding the solubility profile is essential for its applications in pharmaceuticals and medicinal chemistry.

Factors Influencing Solubility:

  • Polarity: The presence of the sulfonamide group contributes to a certain degree of polarity, which can enhance solubility in polar solvents, such as water.
  • Hydrogen Bonding: The amine group may participate in hydrogen bonding with solvents, further influencing solubility behavior.
  • Temperature: As with many chemical compounds, increased temperature can generally lead to increased solubility.

However, it's worth noting that the compound may exhibit limited solubility in organic solvents due to its substantial hydrophobic naphthalene ring. According to various studies, the solubility of sulfonamides tends to vary significantly, so experimental determination is often required to assess solubility accurately.

In practical applications, the solubility characteristics can impact its bioavailability, formulation, and effectiveness. Therefore, when discussing this compound's usage, it's crucial to consider the solubility profile under specific conditions.

Interesting facts

Interesting Facts about N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide

N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide is a fascinating compound with a variety of applications, particularly in the fields of medicinal chemistry and materials science. Here are some key insights:

  • Medicinal Applications: This compound is often studied for its potential use in pharmaceutical formulations. Its sulfonamide group is characteristic of a class of antibiotics, which are crucial in treating bacterial infections.
  • Structure-Activity Relationship: The incorporation of the naphthalene structure gives it unique properties, making it a subject of interest in drug design. The different substituents can significantly affect the biological activity and potency of the compound.
  • Chlorination Benefits: The presence of the chlorine atom in its structure enhances the lipophilicity of the compound, which can improve its absorption and distribution in biological systems.
  • Research Tool: Its ability to interact with certain biological targets makes it a useful tool for researchers investigating mechanisms of action for various therapeutic agents.

As noted by chemical researchers, "Understanding the structure and function of compounds like N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide is critical for advancing new therapeutic strategies." This compound exemplifies the intricate relationship between chemical structure and biological activity, serving as a reminder of the important role chemistry plays in improving human health.

In summation, N-(4-aminobutyl)-5-chloro-naphthalene-1-sulfonamide stands out not only for its chemical properties but also for its contributions to modern science, highlighting the continuous quest for innovative solutions in medicine.

Synonyms
N-(4-aminobutyl)-5-chloronaphthalene-1-sulfonamide
CHEMBL250517
Lopac-A-0666
82657-22-5
NCGC00015031-01
Lopac0_000013
SCHEMBL1929636
DTXSID50274476
BDBM50216684
CCG-204109
N-(4-aminobutyl)-5-chloro-1-naphthalenesulphonamide