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N-(4-aminobutyl)naphthalene-1-sulfonamide

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Identification
Molecular formula
C14H18N2O2S
CAS number
116499-81-7
IUPAC name
N-(4-aminobutyl)naphthalene-1-sulfonamide
State
State

At room temperature, N-(4-aminobutyl)naphthalene-1-sulfonamide is in a solid state, appearing mostly as a crystalline powder.

Melting point (Celsius)
139.00
Melting point (Kelvin)
412.15
Boiling point (Celsius)
563.30
Boiling point (Kelvin)
836.45
General information
Molecular weight
274.37g/mol
Molar mass
274.3680g/mol
Density
1.2500g/cm3
Appearence

N-(4-aminobutyl)naphthalene-1-sulfonamide typically appears as a white crystalline powder. The compound is fairly stable under normal conditions and usually stored in tightly sealed containers to prevent moisture absorption.

Comment on solubility

Solubility of N-(4-aminobutyl)naphthalene-1-sulfonamide (C14H18N2O2S)

N-(4-aminobutyl)naphthalene-1-sulfonamide is a sulfonamide compound that exhibits varying solubility characteristics, dictated primarily by its structural components. Here’s an overview of its solubility properties:

  • Polar Nature: The presence of the sulfonamide functional group enhances its polar characteristics, which generally promotes solubility in polar solvents.
  • Solvent Interactions: This compound is likely to show better solubility in water compared to non-polar solvents due to the possibility of hydrogen bonding and dipole interactions.
  • Temperature Dependence: Solubility can also be affected by temperature; typically, an increase in temperature leads to increased solubility of solid compounds in liquids.
  • pH Influence: The solubility of N-(4-aminobutyl)naphthalene-1-sulfonamide may vary with changes in pH levels, as the protonation state of the amine group can alter its solubility profile.

It is essential to consider these factors when utilizing this compound in various applications, ensuring optimal conditions for its effective use. As with many chemical compounds, understanding the solubility is key to predicting its behavior in different environments and formulations.

Interesting facts

Interesting Facts about N-(4-aminobutyl)naphthalene-1-sulfonamide

N-(4-aminobutyl)naphthalene-1-sulfonamide, often abbreviated as *NABNS*, is a fascinating chemical compound with a variety of applications, especially in the realm of pharmaceuticals and material science. Here are some intriguing aspects:

  • Pharmaceutical Applications: This compound falls under the category of sulfonamides, which are essential in the development of antibiotics. Its unique structure allows it to mimic the substrates of bacterial enzymes, effectively inhibiting their function.
  • Biological Activity: Research has shown that compounds like NABNS possess significant anti-microbial properties, making them useful in the treatment of various infections.
  • Regulatory Role: Sulfonamides such as NABNS can act as *metabolic inhibitors*, impacting the synthesis of folate in bacteria, an essential nutrient they need for growth and replication.
  • Versatility: Beyond medicinal chemistry, NABNS has potential uses in dye chemistry and as a reagent in organic synthesis due to its ability to participate in diverse chemical reactions.
  • Environmental Considerations: The study of sulfonamide compounds, including NABNS, also extends to environmental chemistry as researchers examine their degradation products and overall impact on ecosystems.

As noted by prominent chemists, "The versatility of sulfonamides illustrates the relationship between chemical structure and biological function, paving the way for innovations in drug design." Investigating compounds like N-(4-aminobutyl)naphthalene-1-sulfonamide not only enhances our understanding of chemistry but also highlights the intricate connections between drugs and their biological targets.

Synonyms
CHEMBL251113
N-(4-aminobutyl)naphthalene-1-sulfonamide
SCHEMBL8024067
BDBM50216678
N-(4-aminobutyl)-1-naphthalenesulphonamide