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Napsulon

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Identification
Molecular formula

C14H18N2O2S

CAS number
117-52-2
IUPAC name
N-(4-aminobutyl)naphthalene-2-sulfonamide
State
State

The compound is typically in a solid state at room temperature.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
671.70
Boiling point (Kelvin)
944.85
General information
Molecular weight
278.37g/mol
Molar mass
278.3660g/mol
Density
1.3000g/cm3
Appearence

N-(4-aminobutyl)naphthalene-2-sulfonamide appears as a solid that can vary in form from a crumbling powder to larger crystalline substances. It typically has a white to off-white color. When observed under specific conditions, it may exhibit a slight sheen attributed to the crystalline structure.

Comment on solubility

Solubility of N-(4-aminobutyl)naphthalene-2-sulfonamide

The solubility of N-(4-aminobutyl)naphthalene-2-sulfonamide (C14H18N2O2S) is an intriguing topic due to the compound's unique chemical structure. This sulfonamide derivative exhibits specific solubility characteristics influenced by both its hydrophobic naphthalene core and the hydrophilic sulfonamide group. Here are some key points to consider:

  • Solvent Dependency: N-(4-aminobutyl)naphthalene-2-sulfonamide is generally expected to have greater solubility in polar solvents due to the presence of the sulfonamide group, which can engage in hydrogen bonding.
  • Organic Solvents: It may demonstrate better solubility in organic solvents such as methanol or ethanol compared to non-polar solvents, where the naphthalene moiety predominates.
  • Water Solubility: Its ability to dissolve in water is likely limited, making it more soluble in buffered aqueous solutions where pH can enhance its ionization.
  • Temperature Influence: Solubility often increases with temperature; hence, heating the solution could improve the compound’s dissolution rates in a solvent.

Understanding the solubility of this compound is crucial for its practical applications, as solubility directly impacts its bioavailability and effectiveness in various contexts. As the saying goes, "Like dissolves like," and the balance between polar and non-polar characteristics will dictate how well this compound interacts with various solvents.

Interesting facts

Interesting Facts about N-(4-aminobutyl)naphthalene-2-sulfonamide

N-(4-aminobutyl)naphthalene-2-sulfonamide is a fascinating compound with a variety of applications and properties that make it noteworthy in the field of chemistry. Here are some interesting facts about this sulfonamide derivative:

  • Biomedical Applications: This compound is noteworthy for its potential use in pharmaceuticals. Compounds in the sulfonamide class are often utilized for their antibacterial properties.
  • Structural Features: The naphthalene ring system confers stability and hydrophobic characteristics, which can influence the biological activity of the molecule.
  • Functional Groups: The presence of the amine group provides sites for further chemical modifications, making it a versatile building block in medicinal chemistry.
  • Drug Development: This compound can serve as a model for the development of new therapeutic agents, offering insights into structure-activity relationships.

As a scientist or chemistry student, it is critical to appreciate how such compounds are synthesized and studied in the laboratory. Emphasis is often placed on methods of functionalization and the mechanisms of action of sulfonamides. Notably, researchers are continuously exploring the interplay between structure and functionality, often driving innovation in drug design.

In conclusion, N-(4-aminobutyl)naphthalene-2-sulfonamide exemplifies the synergy between organic chemistry and medicinal applications, illustrating how a simple structural modification can lead to significant biological implications. As the field of chemistry evolves, compounds like this continue to be at the forefront of research and development.

Synonyms
W 12
35517-12-5
N-(4-Aminobutyl)-2-Naphthalenesulfonamide
N-(4-aminobutyl)naphthalene-2-sulfonamide
2-Naphthalenesulfonamide, N-(4-aminobutyl)-
w-12
W-12 Hydrochloride
SCHEMBL1928807
CHEBI:93373
DTXSID20956914
HSCI1_000226
AKOS040754382
BRD-K78084463-003-01-0
Q27165078