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Acetosulfone

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Identification
Molecular formula
C13H14N4O4S
CAS number
88123-07-5
IUPAC name
N-(4-aminophenyl)sulfonyl-N-(3-methoxypyrazin-2-yl)acetamide
State
State

At room temperature, Acetosulfone is in a solid state. It is generally stable under standard laboratory conditions and does not rapidly degrade or react with atmospheric gases.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
346.00
Boiling point (Kelvin)
619.15
General information
Molecular weight
309.33g/mol
Molar mass
309.3300g/mol
Density
1.4600g/cm3
Appearence

Acetosulfone typically appears as an off-white to pale yellow crystalline solid. It may have a slight odor and exists in powdered form. The crystalline nature contributes to its close-packed solid structure.

Comment on solubility

Solubility of N-(4-aminophenyl)sulfonyl-N-(3-methoxypyrazin-2-yl)acetamide

The solubility of N-(4-aminophenyl)sulfonyl-N-(3-methoxypyrazin-2-yl)acetamide is an intriguing aspect of this compound that underlines its potential applications. Generally, solubility can vary significantly depending on various factors, including solvent type, temperature, and pH. Here are some key points to consider:

  • Polar vs. Nonpolar Solvents: The presence of both amine and sulfonyl functional groups suggests that this compound might display better solubility in polar solvents such as water or alcohols.
  • Temperature Influence: Like many organic compounds, solubility often increases with temperature. Therefore, heating the solvent may facilitate greater dissolution of the compound.
  • pH Sensitivity: The solubility of this compound might also be affected by the pH of the solution, especially due to the amino group’s potential to ionize at different pH levels, enhancing solubility in alkaline conditions.

It is often said, "the more you know, the more you find ways to solve problems," and understanding the solubility properties of such compounds can lead to innovative uses in pharmaceuticals and agrochemicals. Predictions suggest that N-(4-aminophenyl)sulfonyl-N-(3-methoxypyrazin-2-yl)acetamide may be relatively soluble when addressed through the right solvents and conditions, granting researchers a valuable tool in exploring its potential applications.

Interesting facts

Interesting Facts about N-(4-aminophenyl)sulfonyl-N-(3-methoxypyrazin-2-yl)acetamide

N-(4-aminophenyl)sulfonyl-N-(3-methoxypyrazin-2-yl)acetamide is a fascinating compound that showcases the intersection of pharmacology and organic chemistry. Here are some interesting points worth noting:

  • Pharmaceutical Relevance: This compound belongs to a class of sulfonamide derivatives, which have been extensively studied for their potential therapeutic applications, especially in the realm of cancer research and anti-inflammatory effects.
  • Mechanistic Study: The unique combination of an aminophenyl group with a methoxypyrazinyl moiety provides intriguing structural attributes that may enhance the compound's activity and selectivity in target environments. Researchers often study the mechanisms through which such compounds interact with biological systems.
  • Functional Groups: The presence of both sulfonyl and acetamide functional groups influences the compound's solubility and bioactivity. These groups can significantly affect the compound's pharmacokinetic properties.
  • Research Potential: Scientists are continually exploring structural modifications to optimize the efficacy and reduce the toxicity of sulfonamide-based compounds, making this particular compound a valuable candidate for ongoing investigation.
  • Multi-faceted Uses: Besides its pharmaceutical potential, compounds structured similarly are often investigated for their role in material sciences, especially in developing agrochemicals.

In summary, N-(4-aminophenyl)sulfonyl-N-(3-methoxypyrazin-2-yl)acetamide is more than just a chemical name; it represents an exciting area of research that merges various disciplines in the life sciences. The ongoing studies and applications of compounds like this reflect the continuous quest for new solutions in medicinal chemistry.

Synonyms
Acetyl sulfamethoxypyrazine
3590-05-4
8SXL21GVKG
UNII-8SXL21GVKG
ACETYLSULFAMETHOXYPYRAZINE
DTXSID50189470
EINECS 222-730-0
FI-6073
ACETYL SULFAMETHOXYPYRAZINE [MI]
N-ACETYL-2-SULFONAMIDO-3-METHOXYPYRAZINE
ACETAMIDE, N-((4-AMINOPHENYL)SULFONYL)-N-(3-METHOXY-2-PYRAZINYL)-
DTXCID80111961
222-730-0
acetylazide
N-(4-aminophenyl)sulfonyl-N-(3-methoxypyrazin-2-yl)acetamide
N-[(P-AMINOPHENYL)SULPHONYL]-N-(3-METHOXYPYRAZINYL)ACETAMIDE
N-((p-Aminophenyl)sulphonyl)-N-(3-methoxypyrazinyl)acetamide
Oprea1_112787
SCHEMBL49915
GWVCIJWBGGVDJJ-UHFFFAOYSA-N
DAA59005
FI6073
AKOS040732374
CS-6615
HY-101575
NS00011886
Q27270972