Interesting facts
Interesting Facts about N-(4-aminophenyl)sulfonylacetamide
N-(4-aminophenyl)sulfonylacetamide, also known by its IUPAC name, is a compound that exhibits a variety of fascinating features making it significant in both pharmaceutical and chemical research. Here are some interesting points:
- Biological Activity: This compound has shown promise in biomedical applications, especially as a potential drug candidate. Its structure suggests it may inhibit certain biological pathways, making it a target for studying anti-inflammatory and analgesic effects.
- Sulfonamide Moiety: The sulfonamide functional group is a key component of this compound. Sulfonamides are known for their antibacterial properties, which have made them crucial in the development of various antibiotics.
- Versatile Reaction Gateway: The presence of both an amine and a sulfonamide group allows the compound to participate in a range of chemical reactions, making it a versatile intermediate for synthesizing other compounds.
- Research Applications: Studies involving this compound often explore its molecular interactions, which can provide insight into drug design and development processes. For example, understanding how it binds to certain proteins can lead to modifications that enhance its efficacy.
- Synthetic Pathways: The methods of synthesizing N-(4-aminophenyl)sulfonylacetamide can involve various techniques, including the use of coupling reagents and protecting groups in organic synthesis. This complexity makes it an interesting study for organic chemists.
- Legacy of Sulfonamide Drugs: Its historical significance is tied to the development of sulfanilamide, the first sulfa drug, which revolutionized medicine and showcased the impact of chemical compounds on human health.
In summary, N-(4-aminophenyl)sulfonylacetamide is not just a compound of interest due to its molecular structure but also because of its potential implications in medicinal chemistry and drug development. As research continues, compounds like this can lead to new discoveries and innovations in the fight against various diseases.
Synonyms
sulfacetamide
144-80-9
Sulphacetamide
Acetosulfamine
N-((4-Aminophenyl)sulfonyl)acetamide
N-Acetylsulfanilamide
N-Sulfanilylacetamide
Acetosulfamin
Albucid
Urosulfon
N-Sulphanilylacetamide
Sulfacetimide
Acetocid
Sulfacet
Sulfanilacetamide
N-(4-aminophenyl)sulfonylacetamide
Formosulfacetamide
Sulphasil
Urosulfone
Albamine
Alesten
Oclucid
Sulamyd
Sulfacyl
Region
Sulfanilazetamid
p-Aminobenzenesulfonacetamide
Sulfacetamida
Sulfacetamidum
Sulphacetamidum
Steramide
Sebizon
Bleph-10
N-Acetyl-4-aminobenzenesulfonamide
Sulf-10
Ophthel-S
p-Aminobenzenesulfonoacetamide
N'-Acetylsulfanilamide
Bleph-10 liquifilm
N-[(4-Aminophenyl)sulfonyl]acetamide
Isopto cetamide
Solfacetamide
OP-Sulfa 30
Sulfacylum
Klaron
Acetamide, N-sulfanilyl-
N1-Acetylsulfanilamide
N-((p-Aminophenyl)sulfonyl)acetamide
N(sup1)-Acetylsulfanilamide
N-Acetylsulfanilamine
A-500
N-(4-Aminophenylsulfonyl)acetamide
Caswell No. 808A
N(sup 1)-Acetylsulfanilamide
N-(4-Aminobenzenesulfonyl)acetamide
Sulfacel-15
Sulfanilamide, N(sup 1)-acetyl-
Sulfacetamidum [INN-Latin]
N(sup 1)-Acetyl-4-aminophenylsulfonamide
SULSTER
Sulfacetamida [INN-Spanish]
N-[(p-Aminophenyl)sulfonyl]acetamide
NSC 63871
CCRIS 6273
N(1)-acetylsulfanilamide
Acetamide, N-((4-aminophenyl)sulfonyl)-
Acetamide, N-[(4-aminophenyl)sulfonyl]-
N-(p-Aminobenzenesulfonyl)acetamide
EINECS 205-640-6
MFCD00066501
NSC-63871
EPA Pesticide Chemical Code 077904
BRN 0981718
FML-S
DTXSID8026060
UNII-4965G3J0F5
CHEBI:63845
AI3-26837
N(1)-acetyl-4-aminophenylsulfonamide
CHEMBL455
4965G3J0F5
Triple sulfa (sulfacetamide)
MLS000069710
DTXCID406060
Sulfacetamide [USP:INN:BAN]
4-14-00-02662 (Beilstein Handbook Reference)
N-acetyl-4-amino-benzenesulfonamide
TRYSUL COMPONENT SULFACETAMIDE
SULTRIN COMPONENT SULFACETAMIDE
VAGILIA COMPONENT SULFACETAMIDE
Sulfacyl (VAN)
GYNE-SULF COMPONENT SULFACETAMIDE
NCGC00018242-04
NCGC00018242-07
SMR000058173
NSC63871
Solfacetamide [DCIT]
Sulfacetamide 100 microg/mL in Acetonitrile
Sulfacetamidum (INN-Latin)
Sulfanilazetamid [German]
Sulfacetamida (INN-Spanish)
SULFACETAMIDE (MART.)
SULFACETAMIDE [MART.]
Sulfacetamide (USP:INN:BAN)
SULFACETAMIDE (USP IMPURITY)
SULFACETAMIDE [USP IMPURITY]
CAS-144-80-9
SULFADIMIDINE IMPURITY E (EP IMPURITY)
SULFADIMIDINE IMPURITY E [EP IMPURITY]
Sulfacetamide (USP/INN)
Sulfacetamid
Sulfacetamide, 1
N-[(4-Aminophenyl)sulfonyl]acetamide; Sulfacetamide; Sulfadimidine Imp. E (Pharmeuropa); Sulfadimidine Impurity E
CETAPRED
PREDAMIDE
Spectrum_000984
Sulfacetamide (Standard)
Opera_ID_1990
Prestwick0_000014
Prestwick1_000014
Prestwick2_000014
Prestwick3_000014
Spectrum2_001318
Spectrum3_001017
Spectrum4_001146
Spectrum5_001230
WLN: ZR DSWMV1
SULFACETAMIDE [MI]
CBChromo1_000180
Sulfanilamide, N1-acetyl-
4-acetylaminosulfonylaniline
SULFACETAMIDE [INN]
NCIOpen2_002838
Sulfacetamide, >=98.0%
Oprea1_686524
Oprea1_810285
SCHEMBL40863
BSPBio_000047
BSPBio_002773
CBDivE_013934
KBioGR_001691
KBioSS_001464
SULFACETAMIDE [VANDF]
MLS001076499
DivK1c_000227
SPECTRUM1500545
SPBio_001415
SPBio_001968
SULFACETAMIDE [WHO-DD]
SULFACETAMIDE [WHO-IP]
BPBio1_000053
GTPL12633
HMS500L09
HY-N7123R
KBio1_000227
KBio2_001464
KBio2_004032
KBio2_006600
KBio3_001993
4-[(acetylamino)sulfonyl]aniline
D10AF06
S01AB04
NINDS_000227
4-[(acetylamino) sulfonyl]aniline
HMS1921A11
HMS2092I13
HMS2232K07
HMS3259G06
HMS3374O02
Pharmakon1600-01500545
SULFACETAMIDE [ORANGE BOOK]
Sulfacetamide, >=98.0% (NT)
HY-N7123
SULFACETAMIDE (TRIPLE SULFA)
Tox21_110846
Tox21_201999
Tox21_303100
AC2473
BBL012083
BDBM50316126
CCG-39256
NSC757323
s5546
STK068185
4-(ACETYLAMINOSULFONYL)ANILINE
SULFACETAMIDUM [WHO-IP LATIN]
AKOS000119729
N-[(4-aminobenzene)sulfonyl]acetamide
Tox21_110846_1
AC-7630
DB00634
FS61457
KS-5327
NC00538
NSC-757323
IDI1_000227
SULFACETAMIDE COMPONENT OF TRYSUL
NCGC00018242-01
NCGC00018242-02
NCGC00018242-03
NCGC00018242-05
NCGC00018242-06
NCGC00018242-08
NCGC00021857-03
NCGC00021857-04
NCGC00021857-05
NCGC00257159-01
NCGC00259548-01
SULFACETAMIDE COMPONENT OF SULTRIN
SULFACETAMIDE COMPONENT OF VAGILIA
N-(P-AMINOPHENYLSULFONYL)ACETAMIDE
SY014752
SBI-0051519.P003
DB-042749
SULFACETAMIDE COMPONENT OF GYNE-SULF
CS-0013812
NS00010528
S0577
EN300-18138
D05947
AB00052094_14
N-ACETYL-4-AMINOBENZENESULFONIC ACID AMIDE
SR-01000000194
Sulfacetamide, VETRANAL(TM), analytical standard
TRIPLE SULFA (SULFACETAMIDE) [ORANGE BOOK]
Q2022983
SR-01000000194-2
BRD-K21520694-001-12-3
BRD-K21520694-001-21-4
BRD-K21520694-236-02-6
N-((4-AMINOPHENYL)SULFONYL)ACETAMIDE [WHO-IP]
Z57202572
205-640-6
Solubility of N-(4-aminophenyl)sulfonylacetamide
N-(4-aminophenyl)sulfonylacetamide (C8H10N2O3S) presents an interesting case in terms of solubility due to its structural features. This compound is expected to have moderate solubility in water, primarily influenced by the following factors:
In comparison with similar compounds, N-(4-aminophenyl)sulfonylacetamide is generally noted for its relatively high solubility in organic solvents, including:
As with many chemical compounds, the solubility can significantly vary based on temperature and pH of the solution. Thus, it is essential to consider these environmental factors when assessing the solubility characteristics of this compound.