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Bupivacaine

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Identification
Molecular formula
C18H28N2O
CAS number
2180-92-9
IUPAC name
N-(4-benzyloxy-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide
State
State

Bupivacaine is typically a solid at room temperature.

Melting point (Celsius)
107.00
Melting point (Kelvin)
380.15
Boiling point (Celsius)
445.00
Boiling point (Kelvin)
718.15
General information
Molecular weight
288.43g/mol
Molar mass
288.4320g/mol
Density
1.0120g/cm3
Appearence

Bupivacaine is generally presented as a white crystalline powder. It is highly soluble in water and alcohol.

Comment on solubility

Solubility of N-(4-benzyloxy-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide

N-(4-benzyloxy-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide is a compound with a complex structure that influences its solubility characteristics significantly. Understanding the solubility of this compound is crucial for its applications in various fields, particularly in pharmaceuticals.

Factors Affecting Solubility

The solubility of this compound can be affected by several factors:

  • Polarity: The presence of polar functional groups, such as the diethylamino group, may enhance solubility in polar solvents.
  • Hydrophobic Regions: The benzyloxy and dimethyl groups contribute to hydrophobic characteristics, which may lead to lower solubility in water.
  • Temperature: Solubility often increases with temperature, particularly for organic compounds.

Solubility in Different Solvents

Generally, this compound is expected to be:

  • More soluble: In organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO).
  • Less soluble: In water due to its hydrophobic components.

Conclusion

In summary, the solubility of N-(4-benzyloxy-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide can be described as moderate in polar organic solvents while likely being limited in aqueous solutions. When considering its use, it is essential to account for these solubility characteristics to optimize conditions for its application.

Interesting facts

Interesting Facts About N-(4-benzyloxy-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide

N-(4-benzyloxy-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide, commonly referred to in scientific circles for its unique structural features, has garnered attention for various reasons:

  • Pharmacological Potential: This compound is often studied for its potential therapeutic effects, particularly in the fields of neurology and psychiatry, given its possible interactions with neurotransmitter systems.
  • Structural Diversity: The compound features a complex molecular structure that incorporates a benzyloxy group, contributing to its hydrophobic character and influencing its solubility and biological activity.
  • Amide Bond: The presence of the amide functional group is significant, as it often plays a crucial role in the stability and reactivity of compounds in biological systems.
  • Diethylamino Group: The diethylamino moiety can enhance the lipophilicity of the molecule, potentially affecting how it crosses biological membranes and interacts with various biological targets.
  • Academic Interest: Such compounds often attract the attention of chemists due to their intricate design, offering numerous possibilities for modification to explore variations in biological activity.

As a student or scientist, understanding the intricacies of compounds like N-(4-benzyloxy-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide is essential for grasping the broader concepts of medicinal chemistry and drug design. The field continually evolves, pushing researchers to explore how modifications can lead to new therapeutic agents.

"The beauty of chemistry lies in its ability to reveal the unpredictable nature of how simple structures can lead to complex behaviors."

Synonyms
BRN 2772670
17060-67-2
2-(Diethylamino)-N-(2,6-dimethyl-4-(phenylmethoxy)phenyl)acetamide
Acetamide, 2-(diethylamino)-N-(2,6-dimethyl-4-(phenylmethoxy)phenyl)-
DTXSID90168901
4-13-00-01857 (Beilstein Handbook Reference)
DTXCID6091392
4'-(Benzyloxy)-2-(diethylamino)-2',6'-acetoxylidide
2',6'-Acetoxylidide, 4'-(benzyloxy)-2-(diethylamino)-(6CI,8CI)
4'-(Benzyloxy)-2-(diethylamino)- 2',6'-acetoxylidide
2',6'-Acetoxylidide, 4'-(benzyloxy)-2-(diethylamino)-