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4'-Bromoacetanilide

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Identification
Molecular formula
C12H15Br2N1O1
CAS number
135-19-3
IUPAC name
N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide
State
State

At room temperature, N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide is typically a solid substance. Due to its crystalline nature, it may form distinct crystals or powder.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
353.00
Boiling point (Kelvin)
626.15
General information
Molecular weight
372.12g/mol
Molar mass
372.1160g/mol
Density
1.7000g/cm3
Appearence

N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide is a solid compound that appears as a white to off-white crystalline powder. Its appearance may vary slightly based on purity and specific laboratory conditions.

Comment on solubility

Solubility of N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide

N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide presents some intriguing aspects regarding its solubility due to its complex structure and the presence of multiple functional groups. The solubility of this compound can be influenced by the following factors:

  • Polarity: The bromine atoms contribute to polar characteristics, while the overall structure, including the aromatic ring and amino groups, also affects its polarity.
  • Solvation: N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide may demonstrate better solubility in polar solvents, such as water or ethanol, compared to non-polar solvents due to the hydrophilic nature of the amino group.
  • Hydrogen Bonding: The presence of the acetamide group allows this compound to engage in hydrogen bonding interactions, which can enhance solubility in protic solvents.

However, consider that solubility is not solely dictated by the chemical structure. Environmental factors such as temperature and pH of the solution can also play significant roles. For example:

  • At increased temperatures, solubility may rise due to enhanced molecular movement.
  • Changes in pH can affect the ionization of the amino group, further altering solubility characteristics.

In summary, while the compound may exhibit some degree of solubility in polar solvents, its solubility can be quite variable depending on the specific conditions. Understanding these nuances is essential for effective application in various chemical environments.

Interesting facts

Exploring N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide

N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide is a remarkable compound with intriguing properties and applications in the field of chemistry. Here are some fascinating aspects of this compound:

  • Role in Cancer Research: This compound falls into the category of potential anticancer agents due to its structural components that can interact with biological systems, making it a subject of investigation in the search for effective cancer therapies.
  • Alkylating Agent: The presence of the brominated ethyl groups allows N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide to act as an alkylating agent, which can modify DNA and impair cell division. Such mechanisms are significant in cancer treatment, though they must be approached with caution due to potential side effects.
  • Ligand Interactions: This compound can function as a ligand, binding to metal ions and catalyzing various chemical reactions. Understanding these interactions enhances our comprehension of catalysis and material science.
  • Historical Significance: Compounds like this have historical importance in the development of synthetic drugs, particularly those targeting severe conditions. Their synthesis has paved the way for modern pharmacology.

"The future of medicine is not in the molecules themselves, but in how we combine them," reflects the philosophy behind research into compounds like N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide. Its unique structure serves as an inspiration for chemists aiming to innovate and expand the frontiers of drug discovery.

Overall, N-[4-[bis(2-bromoethyl)amino]phenyl]acetamide represents just one example of the myriad compounds that challenge us to explore their potential and understand their role in the broader context of chemical science.

Synonyms
2045-17-2
BRN 2811876
ACETANILIDE, 4'-(BIS(2-BROMOETHYL)AMINO)-
4-(Bis(2-bromoethyl)amino)acetanilide
DTXSID30174400
DTXCID6096891
ACETANILIDE,4-(BIS(2-BROMOETHYL)AMINO)-
CHEMBL3246930