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N-[(4-bromo-2,3,5,6-tetramethyl-phenyl)methoxy]benzamide

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Identification
Molecular formula
C18H18BrNO2
CAS number
7411-49-6
IUPAC name
N-[(4-bromo-2,3,5,6-tetramethyl-phenyl)methoxy]benzamide
State
State

N-[(4-bromo-2,3,5,6-tetramethyl-phenyl)methoxy]benzamide is a solid at room temperature, which suggests this compound can be handled easily as a powder or crystalline solid in lab environments.

Melting point (Celsius)
172.50
Melting point (Kelvin)
445.65
Boiling point (Celsius)
482.30
Boiling point (Kelvin)
755.45
General information
Molecular weight
363.23g/mol
Molar mass
363.2260g/mol
Density
1.3300g/cm3
Appearence

This compound is typically a solid at room temperature. It is characterized by its aromatic structure, combining both the bromo-substituted methylphenyl group and the benzamide group. Its appearance can range from white to off-white powder or crystalline solid, depending on its specific level of purity and form.

Comment on solubility

Solubility Characteristics of N-[(4-bromo-2,3,5,6-tetramethyl-phenyl)methoxy]benzamide

N-[(4-bromo-2,3,5,6-tetramethyl-phenyl)methoxy]benzamide, with the chemical formula C18H18BrNO2, exhibits unique solubility properties that depend on various factors such as temperature, solvent type, and molecular interactions. Here are several key points regarding its solubility:

  • Polarity: The compound contains both hydrophobic and hydrophilic components, contributing to its moderate solubility in organic solvents.
  • Solvents: It is likely to be soluble in non-polar to moderately polar organic solvents such as:
    • Chloroform
    • Ethyl acetate
    • Toluene
  • Water Solubility: Due to the presence of bromo and amide functional groups, water solubility may be limited, as typically observed with compounds that are more hydrophobic.
  • Temperature Influence: Solubility can vary significantly with temperature, where higher temperatures may increase solubility in organic solvents.

In summary, while N-[(4-bromo-2,3,5,6-tetramethyl-phenyl)methoxy]benzamide is not expected to be highly soluble in water, it displays sufficient solubility in organic solvents, making it amenable for various applications in organic chemistry and related fields. Understanding these solubility dynamics is crucial for effective experimental design and formulation.

Interesting facts

Exciting Insights into N-[(4-Bromo-2,3,5,6-tetramethyl-phenyl)methoxy]benzamide

N-[(4-Bromo-2,3,5,6-tetramethyl-phenyl)methoxy]benzamide is a compound that presents a fascinating intersection of chemistry, medicinal potential, and synthetic methodology. Here are some interesting facts about this intriguing compound:

  • Structural Complexity: This compound features a bromo substituent and a methoxy group, which significantly influence its chemical reactivity and interactions with biological systems.
  • Biological Relevance: Compounds similar to benzamides have shown promise in medicinal chemistry, often serving as candidates for drug development, especially in the fields of cancer and neurology.
  • Utility in Organic Synthesis: The incorporation of bulky substituents, like tetramethyl, enhances steric hindrance, making this compound an interesting subject of study for chemists interested in the electronic and steric effects on reactivity.
  • Role in Material Science: Due to its unique properties, derivatives of this compound may find applications in the development of new polymers or advanced materials.

Studies suggest that the bromo group in the compound can act as a vital handle for subsequent chemical transformations, making it a scaffold for developing various derivatives with potentially unique properties. Researchers are continually exploring its potential applications to leverage its unique structural characteristics.

In summary, N-[(4-Bromo-2,3,5,6-tetramethyl-phenyl)methoxy]benzamide is more than just a chemical formula; it represents the confluence of creativity and science in the laboratory. As the field of chemistry progresses, compounds like this one may hold the key to unlocking new innovations.

Synonyms
HDInhib_000075
CBChromo1_000118
CBChromo1_000262
CBDivE_016184
SCHEMBL5611067