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Bupivacaine

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Identification
Molecular formula
C18H28BrN3O
CAS number
38396-39-3
IUPAC name
N-(4-bromo-2,6-dimethyl-phenyl)-2-(dibutylamino)acetamide
State
State

At room temperature, N-(4-bromo-2,6-dimethylphenyl)-2-(dibutylamino)acetamide is a solid.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
325.28g/mol
Molar mass
325.2830g/mol
Density
1.0500g/cm3
Appearence

The compound N-(4-bromo-2,6-dimethylphenyl)-2-(dibutylamino)acetamide appears as a white crystalline powder. It is typically utilized in its hydrochloride form, which is also a white crystalline substance with good solubility in water, leading to clear solutions when dissolved.

Comment on solubility

Solubility of N-(4-bromo-2,6-dimethyl-phenyl)-2-(dibutylamino)acetamide

N-(4-bromo-2,6-dimethyl-phenyl)-2-(dibutylamino)acetamide is a compound with interesting solubility characteristics that can be influenced by its chemical structure. The solubility profile is typically affected by several factors, including:

  • Polarity: The presence of both hydrophobic dibutyl groups and a polar acetamide group suggests a mixed polarity, which may lead to variable solubility in different solvents.
  • Solvent Choice: Its likely improved solubility in organic solvents (like ethanol or dichloromethane) compared to polar solvents (like water) due to hydrophobic interactions.
  • Temperature: Solubility may increase with temperature, as is common with many organic compounds.
  • pH Effects: If the compound forms ions or interacts with solvents at certain pH levels, this may also influence solubility.

Overall, one might say that "solubility is a dance between polarity, temperature, and solvent interactions"! Therefore, examining solubility under various conditions can yield critical insights for practical applications in formulations and chemical reactions.

Interesting facts

Interesting Facts about N-(4-bromo-2,6-dimethyl-phenyl)-2-(dibutylamino)acetamide

N-(4-bromo-2,6-dimethyl-phenyl)-2-(dibutylamino)acetamide is a compound that intrigues many in the field of organic chemistry due to its unique structure and potential applications. Here are some compelling insights:

  • Pharmaceutical Relevance: This compound belongs to a class of compounds often explored for their medicinal properties. The presence of the dibutylamino moiety suggests possible uses in drug formulations aimed at enhancing solubility or bioavailability.
  • Structural Complexity: The presence of both bromine and multiple methyl groups in its structure allows for interesting steric interactions, which can affect its reactivity and target specificity in biological systems.
  • Potential Applications: Compounds with similar frameworks are often investigated for functions such as antidepressants, anxiolytics, or other neurological agents, presenting a rich area for research.
  • Synthesis Challenges: Creating this molecule can pose significant synthetic hurdles, especially relating to the bromination and the introduction of the dibutylamino group, showcasing the ingenuity and creativity required in synthetic organic chemistry.
  • Research Insights: Studies have shown that modifications in the structure, like altering the position of bromine or the length of alkyl chains, can lead to significant changes in the compound's pharmacological profile.

In conclusion, N-(4-bromo-2,6-dimethyl-phenyl)-2-(dibutylamino)acetamide is more than just an organic compound; it represents the intersection of advanced chemistry and potential real-world applications in medicine and beyond. As researchers continue to explore and synthesize derivatives of this compound, the possibilities for discovery are vast and exciting!

Synonyms
A 1414
2',6'-ACETOXYLIDIDE, 4'-BROMO-2-(DIBUTYLAMINO)-
17060-82-1
4'-Bromo-2-(dibutylamino)-2',6'-acetoxylidide
DTXSID00168912
DTXCID8091403