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N-(4-bromophenyl)-2-fluoroacetamide

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Identification
Molecular formula
C8H7BrFNO
CAS number
91587-40-3
IUPAC name
N-(4-bromophenyl)-2-fluoro-acetamide
State
State

At room temperature, N-(4-bromophenyl)-2-fluoroacetamide is in a solid state, typically utilized within research and chemical applications given its structured stability and form.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
291.30
Boiling point (Kelvin)
564.45
General information
Molecular weight
232.05g/mol
Molar mass
232.0440g/mol
Density
1.6300g/cm3
Appearence

N-(4-bromophenyl)-2-fluoroacetamide typically appears as a solid crystalline substance. Its color ranges from white to slightly off-white, indicative of its purity.

Comment on solubility

Solubility of N-(4-bromophenyl)-2-fluoro-acetamide

N-(4-bromophenyl)-2-fluoro-acetamide, with the formula C9H8BrFNO, presents interesting solubility characteristics that are influenced by its molecular structure. This compound contains both polar and nonpolar functional groups, which affects how it interacts with solvents.

Typically, one can observe the following regarding its solubility:

  • Polar solvents: Due to the presence of the amide functional group, N-(4-bromophenyl)-2-fluoro-acetamide tends to be soluble in polar solvents such as water and ethanol. The molecule's polar nature allows it to engage in hydrogen bonding with these solvents.
  • Nonpolar solvents: Conversely, its aromatic structure may lead to relatively poor solubility in nonpolar solvents like hexane or octane. The hydrophobic part of the molecule does not favor interaction with nonpolar environments.
  • Temperature effects: As is common with many organic compounds, solubility can increase with temperature. Thus, heating the solvent may enhance the solubility of this compound.

In summary, the solubility profile of N-(4-bromophenyl)-2-fluoro-acetamide showcases the delicate balance between its polar and nonpolar characteristics, making it a fascinating subject for research. Always remember: "Solubility is a key factor in the behavior of compounds in solution."

Interesting facts

Intriguing Insights into N-(4-bromophenyl)-2-fluoro-acetamide

N-(4-bromophenyl)-2-fluoro-acetamide is a fascinating compound, notable for its diverse applications in the field of medicinal chemistry and agriculture. Here are some interesting facts:

  • Pharmaceutical Potential: The presence of both bromine and fluorine substituents enhances the lipophilicity of the molecule, potentially improving its ability to interact with biological membranes. This makes it a subject of interest for drug development, particularly in seeking new treatments for a variety of diseases.
  • Mechanism of Action: Compounds with similar structures often inhibit specific enzymes or proteins in biological systems. This mechanism can be pivotal in understanding how to design more effective therapeutic agents.
  • Role in Agricultural Chemistry: This compound could possess herbicidal or fungicidal properties, making it valuable in the agricultural sector. Studying its efficacy and safety can lead to more sustainable agricultural practices.
  • Structure-Activity Relationship (SAR): The unique combination of a bromophenyl and a fluoro-acetamide group allows chemists to explore the SAR, aiding in the optimization of lead compounds for enhanced biological activity.
  • Research Challenges: As with many fluorinated compounds, synthesis can be challenging due to the stability and reactivity of the fluorine atom. Understanding these challenges can be crucial for developing more effective synthetic methodologies.

In summary, N-(4-bromophenyl)-2-fluoro-acetamide illustrates the intricate relationship between molecular structure and biological efficacy, showcasing the beauty of chemistry in developing solutions for real-world applications. As research continues, we may uncover even more about the potential of this compound, paving the way for innovative discoveries in science and industry.

Synonyms
N-(4-Bromophenyl)-2-fluoroacetamide
Yanomite
Fluoroaceto-p-bromoanilide
4'-Bromo-2-fluoroacetanilide
351-05-3
BRN 2718782
Acetamide, N-(4-bromophenyl)-2-fluoro-
ACETANILIDE, 4'-BROMO-2-FLUORO-
DTXSID40188593
4-12-00-01505 (Beilstein Handbook Reference)
FABA
Acetamide, N-(4-bromophenyl)-2-fluoro- (9CI)
SCHEMBL3472843
DTXCID00111084
ACCDBHBOYZJSDT-UHFFFAOYSA-N
Acetamide, N-(4-bromophenyl)-2-fluoro-(9CI)