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N-(4-bromophenyl)formamide

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Identification
Molecular formula
C7H6BrNO
CAS number
23445-18-1
IUPAC name
N-(4-bromophenyl)formamide
State
State

At room temperature, N-(4-bromophenyl)formamide is in a solid state. It is stable under normal conditions but should be stored in a cool, dry place away from incompatible substances.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
214.04g/mol
Molar mass
214.0370g/mol
Density
1.5787g/cm3
Appearence

N-(4-bromophenyl)formamide is a solid compound that typically appears as off-white to light tan crystalline powder. It lacks any distinctive odor and its physical form makes it relatively easy to handle in laboratory settings.

Comment on solubility

Solubility of N-(4-bromophenyl)formamide

N-(4-bromophenyl)formamide, with the chemical formula C7H6BrNO, exhibits interesting solubility characteristics that are influenced by its molecular structure. This compound is known to have:

  • Moderate solubility in polar solvents: It dissolves readily in solvents such as water and alcohol due to its ability to form hydrogen bonds.
  • Limited solubility in non-polar solvents: Conversely, its solubility in non-polar organic solvents is quite low, which is typical for compounds with polar functional groups.

As noted in various studies, the presence of the bromine substituent acts as an electronegative atom, enhancing the molecule's polarity. This leads to:

  • Increased interaction with water molecules, promoting solubility.
  • Reduced solubility in non-polar environments due to lack of favorable interactions.

In summary, while the solubility of N-(4-bromophenyl)formamide in polar solvents is advantageous for applications in organic chemistry, its behavior in non-polar solvents reflects a common trend seen in such polar compounds.

Interesting facts

Interesting Facts about N-(4-bromophenyl)formamide

N-(4-bromophenyl)formamide is a fascinating organic compound that showcases the intriguing chemistry of amides and their derivatives. Here are some significant points that highlight its importance:

  • Structure and Functionality: This compound features a 4-bromophenyl group attached to a formamide moiety, making it a pivotal compound in the study of aromatic amides. The bromine atom enhances the electron-withdrawing nature of the aromatic ring, influencing its chemical reactivity.
  • Role in Organic Synthesis: N-(4-bromophenyl)formamide acts as a versatile intermediate in the synthesis of various pharmaceuticals and agrochemicals. Such compounds are often employed to develop new materials with desired biological activity.
  • Biological Relevance: Many derivatives of formamide have been studied for their biological activities, including antimicrobial and antitumor properties. Research into N-(4-bromophenyl)formamide may reveal potential therapeutic applications.
  • Polarity and Solvation: The presence of both the polar carbonyl group and the aromatic bromine substituent can create unique solvation properties, affecting how the compound interacts with solvents and other chemicals.

As a compound rich in potential applications, N-(4-bromophenyl)formamide serves as a prime example of how structural nuances change the behavior and utility of chemical entities. Its study not only provides insights into basic chemical principles but also bridges the gap between organic synthesis and applied chemistry.

In the words of renowned chemist Linus Pauling, "Chemistry is the common thread that connects all of science." In this context, N-(4-bromophenyl)formamide exemplifies how a simple modification can lead to a wide-reaching impact in the field of chemical research and application.

Synonyms
N-(4-Bromophenyl)formamide
Formamide, N-(4-bromophenyl)-
p-Bromoformanilide
4-Bromoformanilide
Formic acid p-bromophenylamide
FORMANILIDE, 4'-BROMO-
p-Bromfenylamid kyseliny mravenci
NSC 1180
BRN 2802372
p-Bromfenylamid kyseliny mravenci [Czech]
DTXSID40180794
DTXCID80103285
Formamide, N-(4-bromophenyl)-(9CI)
623-863-0
2617-78-9
E94N49UNV3
NSC-1180
p-Brom-formanilid
para-Bromoformanilide
4-Bromophenylformamide
Formamide, N-(4-bromophenyl)- (9CI)
(4-bromophenyl)formamide
4-Bromophenylformamide #
UNII-E94N49UNV3
N-(4-Bromophenyl)-formamide
SCHEMBL515529
N-(4-bromo-phenyl)-formamide
N-FORMYL-4-BROMOANILINE
NSC1180
N-(4-Bromophenyl)formamide, 97%
STK366698
AKOS005443023
AS-86528
CS-0336137
G86120
AE-641/02550056
F2108-0262