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N-(4-carbamimidoyl-3-chloro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide

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Identification
Molecular formula
C16H14ClIN3O2
CAS number
123456-78-9
IUPAC name
N-(4-carbamimidoyl-3-chloro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide
State
State

At room temperature, this compound is a solid. It maintains its crystallinity until approaching its melting point, at which it transitions to a liquid state. The solid nature is due to strong intermolecular forces, including hydrogen bonds, which stabilize the structure.

Melting point (Celsius)
229.00
Melting point (Kelvin)
502.15
Boiling point (Celsius)
545.00
Boiling point (Kelvin)
818.15
General information
Molecular weight
420.99g/mol
Molar mass
420.9900g/mol
Density
2.1000g/cm3
Appearence

The compound typically presents as a crystalline solid. Its appearance may range from a pale yellow to white, depending on the purity and specific synthesis conditions. In some cases, it may also appear slightly beige due to the presence of trace impurities. The crystalline structure may be observed under a microscope, showcasing defined edges and facets.

Comment on solubility

Solubility of N-(4-carbamimidoyl-3-chloro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide

The solubility profile of the compound N-(4-carbamimidoyl-3-chloro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide (C16H14ClIN3O2) can be quite insightful given its complex structure.

Factors Influencing Solubility

Several factors play a crucial role in determining the solubility of this compound:

  • Polarity: The presence of functional groups such as hydroxyl (–OH) and amide (–CONH2) can enhance solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds is significant; this compound can engage in hydrogen bonding due to its hydroxyl and amide groups.
  • Halo and Aromatic Effects: The chloro and iodo substituents may add to the hydrophobic character, possibly influencing solubility in organic solvents.

Solubility Characteristics

The resulting solubility can be summarized as follows:

  • Likely soluble in polar solvents like water and alcohols.
  • May show moderate solubility in less polar organic solvents due to the aromatic character.
  • Overall, solubility will be influenced by temperature and pH of the medium.

In conclusion, while specific solubility values may vary, this compound's solubility is expected to exhibit features common to molecules containing both hydrophilic and hydrophobic characteristics, making it versatile in various solvent environments.

Interesting facts

Interesting Facts about N-(4-carbamimidoyl-3-chloro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide

N-(4-carbamimidoyl-3-chloro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide is a fascinating compound with numerous applications in the field of medicinal chemistry and pharmaceuticals. This intricate molecule is characterized by its unique combination of functional groups, which bestow upon it interesting biological properties.

Key Highlights:

  • Diverse Biological Activity: This compound is part of a class of molecules that are often investigated for their potential pharmacological effects, particularly in acting as inhibitors or modulators of various biological pathways.
  • Structural Complexity: The presence of multiple heavy atoms such as iodine and chlorine makes this compound particularly intriguing for studies involving organohalogen chemistry and its perturbative effect on biological systems.
  • Applications in Drug Development: Compounds like this are often explored for their potential roles in treating diseases, particularly in targeting specific enzymes or receptors in therapeutic areas.
  • Synthetic Challenges: The synthesis of this compound can present unique challenges, especially in achieving the desired selectivity and yield due to its complex structure, making it an interesting case study for synthetic chemists.

Moreover, as a research chemist or a student exploring new compounds, one might find it captivating to analyze the reactivity patterns of the functional groups present in N-(4-carbamimidoyl-3-chloro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide. Each substituent can influence the molecule’s overall behavior, affecting not only its stability but also its interaction with biological macromolecules.

As noted by chemists in the field, "The specificity of a compound often lies in its structure, and understanding these relationships paves the way for innovative drug design." This quote underscores the significance of compounds like this in the broader scope of medicinal chemistry.

In conclusion, N-(4-carbamimidoyl-3-chloro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide stands out as a compound worthy of exploration, embodying the journey of discovery present in the world of chemical research.

Synonyms
n-(4-carbamimidoyl-3-choro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide
N-(4-carbamimidoyl-3-chlorophenyl)-2-hydroxy-3-iodo-5-methylbenzamide
CHEMBL62897
1gjd
BDBM14159
APC-11421
DB06857
PD005855
NS00069134
Q27095762
N-{4-[amino(imino)methyl]-3-chlorophenyl}-2-hydroxy-3-iodo-5-methylbenzamide