N-(4-chlorophenyl)-2-fluoroacetamide

Interesting Facts about N-(4-chlorophenyl)-2-fluoro-acetamide

N-(4-chlorophenyl)-2-fluoro-acetamide, often abbreviated as CFPA, is a fascinating compound that has garnered attention in the fields of pharmaceuticals and organic synthesis. Here are some notable aspects of this compound:

• Pharmaceutical Significance: CFPA serves as an important intermediate in the synthesis of various drugs, particularly in the search for effective treatments for ailments such as cancer and bacterial infections.
• Structure-Activity Relationship: The presence of both the chlorophenyl and fluoro substituents greatly influences the biological activity of the compound. This leads researchers to study how modifications affect therapeutic efficacy.
• Fluorine's Role: The fluorine atom contributes to increased lipophilicity, which can facilitate better membrane permeability—an essential factor in drug design.
• Synthetic Pathways: The synthesis of CFPA often involves strategic reactions such as nucleophilic acyl substitution, which illustrates the elegance and complexity of organic chemistry.
• Applications Beyond Medicine: Beyond its pharmaceutical applications, CFPA is also used in materials science, where it can play a role in developing new polymers and other functional materials.

In conclusion, N-(4-chlorophenyl)-2-fluoro-acetamide is not just another compound; its unique structural features and varied applications make it a subject of great interest in modern chemistry. As researchers continue to explore its potential, CFPA remains a prime example of how chemical compounds can have far-reaching implications across multiple scientific disciplines.