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Chlorphenamine

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Identification
Molecular formula
C16H19ClN2
CAS number
132-22-9
IUPAC name
N'-[(4-chlorophenyl)-phenyl-methyl]-N-(2,6-dimethylphenyl)ethane-1,2-diamine
State
State

At room temperature, chlorphenamine is typically a solid. It is often utilized in the form of tablets or capsules for therapeutic purposes.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
404.60
Boiling point (Kelvin)
677.80
General information
Molecular weight
303.83g/mol
Molar mass
303.8330g/mol
Density
1.0870g/cm3
Appearence

The compound typically appears as a white or slightly off-white crystalline solid. It is often found in powdered form for medicinal formulations.

Comment on solubility

Solubility of N'-[(4-chlorophenyl)-phenyl-methyl]-N-(2,6-dimethylphenyl)ethane-1,2-diamine

The solubility of N'-[(4-chlorophenyl)-phenyl-methyl]-N-(2,6-dimethylphenyl)ethane-1,2-diamine can be described as follows:

  • Polarity: This compound contains both hydrophobic (aromatic rings) and hydrophilic (amine groups) characteristics, leading to an interesting balance in terms of solubility.
  • Solvent Compatibility: Generally, compounds with significant aromatic content tend to be more soluble in organic solvents such as ethanol, dichloromethane, or acetone than in water due to the non-polar character of the aromatic rings.
  • Temperature Factor: As with many organic compounds, solubility may increase with temperature, making it more soluble in warm solvents compared to cold.

Overall, while N'-[(4-chlorophenyl)-phenyl-methyl]-N-(2,6-dimethylphenyl)ethane-1,2-diamine may have limited solubility in water, it is more likely to dissolve effectively in non-polar or mildly polar organic solvents, indicating the complex interplay of its molecular structure and solvent interactions.

Interesting facts

Interesting Facts about N'-[(4-chlorophenyl)-phenyl-methyl]-N-(2,6-dimethylphenyl)ethane-1,2-diamine

This compound, with its complex structure, is an intriguing example of a diamine derivative. Here are some remarkable aspects worth noting:

  • Pharmaceutical Potential: Compounds like this one are often synthesized for their potential use in developing new pharmaceuticals. The presence of the chlorophenyl and dimethylphenyl groups suggests that it may interact with various biological targets, potentially leading to therapeutic applications.
  • Synthetic Chemistry: The synthesis of such compounds typically involves multi-step reactions that require careful consideration of functional group transformations. This highlights the skills required in organic synthesis and the importance of functional group compatibility.
  • Structure-Activity Relationship: Understanding how structural changes in similar compounds influence biological activity is a critical area of research. This compound may provide insights into how the arrangement of chlorinated and methylated phenyl rings affects its efficacy.
  • Environmental Impact: The presence of halogens, such as chlorine, in organic compounds often raises questions about environmental sustainability. Researchers are increasingly focused on minimizing the ecological footprint of chemical processes, making this an important consideration for compounds like this one.
  • Analytical Techniques: Characterization of such complex molecules typically employs various analytical techniques, including NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry), which can provide insight into both structural composition and purity.

As a scientist or a chemistry student, engaging with compounds like N'-[(4-chlorophenyl)-phenyl-methyl]-N-(2,6-dimethylphenyl)ethane-1,2-diamine fosters a deeper understanding of both theoretical and practical aspects of organic chemistry. The interplay between synthesis, analysis, and application makes this field a dynamic and exciting area of study.