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Chlorphenamine

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Identification
Molecular formula
C16H19ClN2
CAS number
132-22-9
IUPAC name
N'-[(4-chlorophenyl)-phenyl-methyl]-N-cyclohexyl-ethane-1,2-diamine
State
State

Chlorphenamine is generally found in a solid state at room temperature.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.20
Boiling point (Celsius)
352.40
Boiling point (Kelvin)
625.60
General information
Molecular weight
274.79g/mol
Molar mass
274.8200g/mol
Density
1.0300g/cm3
Appearence

Chlorphenamine is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of N'-[(4-chlorophenyl)-phenyl-methyl]-N-cyclohexyl-ethane-1,2-diamine

The solubility of N'-[(4-chlorophenyl)-phenyl-methyl]-N-cyclohexyl-ethane-1,2-diamine can be influenced by several factors due to its complex organic structure. This compound is characterized by a hydrophobic cyclohexyl group and a phenyl ring, which typically suggests limited solubility in polar solvents. Here are some key points regarding its solubility:

  • Polar Solvents: It is expected to have low solubility in water due to its hydrophobic characteristics.
  • Non-Polar Solvents: The compound may exhibit better solubility in organic solvents such as ethanol, chloroform, or dichloromethane.
  • Temperature Effects: Like many organic compounds, solubility may increase with higher temperatures, allowing for greater molecular movement in polar and non-polar solvents.
  • Structure Influence: The presence of the chlorophenyl group can affect interactions with solvent molecules, potentially enhancing solubility in certain non-polar environments.

In conclusion, while N'-[(4-chlorophenyl)-phenyl-methyl]-N-cyclohexyl-ethane-1,2-diamine is likely largely insoluble in water, its solubility in various organic solvents can vary significantly and should be explored through empirical testing for practical applications.

Interesting facts

Interesting Facts about N'-[(4-chlorophenyl)-phenyl-methyl]-N-cyclohexyl-ethane-1,2-diamine

N'-[(4-chlorophenyl)-phenyl-methyl]-N-cyclohexyl-ethane-1,2-diamine is a fascinating organic compound that belongs to the class of diamines, which are distinguished by the presence of two amine groups within their structure. This compound showcases unique characteristics that make it interesting for various fields, particularly medicinal chemistry and drug development.

Key Features:

  • Structural Diversity: The compound features a cyclohexyl group which contributes to its steric profile, enhancing its interaction capabilities with biological targets.
  • Chlorine Substitution: The presence of a 4-chlorophenyl group serves not only as a viable site for pharmacological activity but also influences the compound's lipophilicity, which in turn affects membrane permeability.
  • Biological Applications: Compounds of this nature are often investigated for their potential as therapeutic agents, especially in treating conditions related to neurology and psychiatry.

Its molecular architecture provides insights into the ways in which small modifications to functional groups can alter biological activity or pharmacokinetic properties. Researchers often quote that "small structural changes can lead to significant functional shifts," and this compound exemplifies that principle beautifully.

Research Potential:

  • Drug Design: Its structural elements are prime candidates for lead compound synthesis in drug discovery programs.
  • Mechanistic Studies: The unique amine interaction potential allows for comprehensive mechanistic studies, paving the way for innovative therapeutic approaches.

In summary, N'-[(4-chlorophenyl)-phenyl-methyl]-N-cyclohexyl-ethane-1,2-diamine represents much more than a mere chemical entity; it is a gateway to understanding how modifications at the molecular level can influence biological systems and therapeutic efficacy. As scientists continue to explore its properties, this compound may well contribute to the next generation of pharmacological breakthroughs.

Synonyms
N-(alpha-(p-Chlorophenyl)benzyl)-N'-cyclohexylethylenediamine
23892-45-7
ETHYLENEDIAMINE, N-(alpha-(p-CHLOROPHENYL)BENZYL)-N'-CYCLOHEXYL-
RefChem:345271
DTXSID90946680
N~1~-[(4-Chlorophenyl)(phenyl)methyl]-N~2~-cyclohexylethane-1,2-diamine