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Chlorphenamine

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Identification
Molecular formula
C16H19ClN2
CAS number
132-22-9
IUPAC name
N-[(4-chlorophenyl)-phenyl-methyl]-N',N'-dipropyl-ethane-1,2-diamine
State
State

At room temperature, chlorphenamine is typically found in a solid state.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.10
Boiling point (Celsius)
246.80
Boiling point (Kelvin)
519.90
General information
Molecular weight
300.84g/mol
Molar mass
300.8390g/mol
Density
0.9988g/cm3
Appearence

Chlorphenamine, commonly known as Chlorpheniramine, appears as a white to off-white crystalline powder that is generally odorless.

Comment on solubility

Solubility of N-[(4-chlorophenyl)-phenyl-methyl]-N',N'-dipropyl-ethane-1,2-diamine

The solubility of N-[(4-chlorophenyl)-phenyl-methyl]-N',N'-dipropyl-ethane-1,2-diamine can be characterized by several important factors:

  • Polarity: The presence of both polar and nonpolar groups in the compound suggests a potential for varied solubility in different solvents.
  • Hydrogen Bonding: The amine groups (-NH) can form hydrogen bonds with solvents that can accept or donate hydrogen bonds, such as water, possibly enhancing its solubility in polar solvents.
  • Solvent Compatibility: Generally, due to its larger hydrophobic regions, the compound may exhibit limited solubility in highly polar solvents like water, while showing better solubility in organic solvents such as ethanol or dichloromethane.
  • Temperature Effects: Temperature changes can significantly affect solubility, with increased temperatures often enhancing the solubility of organic compounds.

In summary, while N-[(4-chlorophenyl)-phenyl-methyl]-N',N'-dipropyl-ethane-1,2-diamine may exhibit some degree of solubility in polar solvents due to its functional groups, its overall solubility is likely limited. Further experiments would be necessary to obtain precise measurements and to delineate specific solvent interactions.

Interesting facts

Interesting Facts about N-[(4-chlorophenyl)-phenyl-methyl]-N',N'-dipropyl-ethane-1,2-diamine

N-[(4-chlorophenyl)-phenyl-methyl]-N',N'-dipropyl-ethane-1,2-diamine is a fascinating compound with several intriguing aspects worth exploring.

Chemical Structure and Properties

This compound belongs to the class of diamines, characterized by the presence of two amine groups in its structure. The distinctive features of this compound include:

  • Chlorine Substitution: The presence of a chlorine atom on the phenyl ring (4-chlorophenyl) contributes to the compound's reactivity and potential applications in various fields.
  • Propyl Substitution: The dipropyl amine functionality enhances the compound's lipophilicity, making it more soluble in organic solvents compared to its primary amine counterparts.

Applications in Research and Industry

This compound serves as a valuable building block in medicinal chemistry. Some notable applications include:

  • Pharmaceutical Development: Compounds containing similar structures are often investigated for their biological activity, including potential anticancer and antidepressant properties.
  • Material Science: Due to its specific molecular conformation, this compound may be explored for use in polymer science or as a precursor for creating novel materials.

Biological Significance

Interestingly, the incorporation of a chloro group can affect the biological activity of the compound. As noted by researchers, "halogenated compounds often exhibit unique interactions with biological systems." This emphasizes the importance of structural modifications in the design of drug candidates.

Conclusion

In summary, N-[(4-chlorophenyl)-phenyl-methyl]-N',N'-dipropyl-ethane-1,2-diamine exemplifies the complexity and potential of organic compounds in both scientific research and practical applications. Its unique structure and properties open the door to numerous possibilities in chemistry and related fields.

Synonyms
23892-36-6
N-(alpha-(p-Chlorophenyl)benzyl)-N',N'-dipropylethylenediamine
ETHYLENEDIAMINE, N-(alpha-(p-CHLOROPHENYL)BENZYL)-N',N'-DIPROPYL-
RefChem:345270
DTXSID00946676
N~2~-[(4-Chlorophenyl)(phenyl)methyl]-N~1~,N~1~-dipropylethane-1,2-diamine