Skip to main content

Chlorpheniramine

ADVERTISEMENT
Identification
Molecular formula
C16H19ClN2
CAS number
132-22-9
IUPAC name
N'-[(4-chlorophenyl)-phenyl-methyl]ethane-1,2-diamine
State
State

At room temperature, chlorpheniramine is typically found in a solid state.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.00
Boiling point (Celsius)
426.10
Boiling point (Kelvin)
699.30
General information
Molecular weight
274.80g/mol
Molar mass
274.7950g/mol
Density
1.1260g/cm3
Appearence

Chlorpheniramine is a white to off-white crystalline powder. It may appear in solid forms such as tablets or capsules when prepared for pharmaceutical uses.

Comment on solubility

Solubility Insights for N'-[(4-chlorophenyl)-phenyl-methyl]ethane-1,2-diamine

N'-[(4-chlorophenyl)-phenyl-methyl]ethane-1,2-diamine, with its complex structure, exhibits unique solubility characteristics that can influence its applications in various fields. Understanding its solubility is crucial for effective utilization. Here are some key points regarding its solubility:

  • Polarity: The presence of the diamine functional group contributes to polar interactions, potentially enhancing solubility in polar solvents such as water.
  • Solvent Compatibility: It is expected to show solubility in organic solvents, such as ethanol and dimethyl sulfoxide (DMSO), due to the aromatic nature of the chlorophenyl and phenyl groups.
  • Hydrogen Bonding: The amine groups facilitate hydrogen bonding, making the compound more soluble in aqueous solutions, though the extent may vary based on the solvent's nature and temperature.
  • Temperature Dependency: Like many chemical compounds, the solubility may increase with temperature; thus, testing at various temperatures is advisable for optimal dissolution.

In conclusion, while N'-[(4-chlorophenyl)-phenyl-methyl]ethane-1,2-diamine can be expected to be soluble in both polar and non-polar solvents, experimental verification is essential for precise applications. Its solubility characteristics are fundamental for understanding how it behaves in different environments, thus aiding in effective formulation and use.

Interesting facts

Interesting Facts about N'-[(4-Chlorophenyl)-Phenyl-Methyl]Ethane-1,2-Diamine

N'-[(4-chlorophenyl)-phenyl-methyl]ethane-1,2-diamine is a fascinating compound that plays a significant role in medicinal chemistry and organic synthesis. Here are some interesting aspects to consider:

  • Structural Complexity: This compound belongs to the class of aromatic amines, which are characterized by the presence of amino groups (-NH2) attached to aromatic rings. Its structure includes multiple functional groups that contribute to its reactivity and potential applications.
  • Biological Relevance: Compounds with similar structures have been studied for their pharmacological properties. They often serve as intermediates in the synthesis of pharmaceuticals and agrochemicals.
  • Substituent Effects: The presence of the 4-chlorophenyl group can significantly influence the compound's electronegativity, hydrophobicity, and overall biological activity, making it an intriguing subject for further investigation.
  • Synthetic Pathways: The synthesis of this compound typically involves the reaction of phenyl derivatives with amines under specific conditions. This highlights the importance of understanding reaction mechanisms and conditions in organic chemistry.
  • Research Applications: With ongoing research, compounds like N'-[(4-chlorophenyl)-phenyl-methyl]ethane-1,2-diamine can contribute to the development of new drugs, especially in areas such as cancer therapy and antibacterial agents.

In summary, N'-[(4-chlorophenyl)-phenyl-methyl]ethane-1,2-diamine is more than just a chemical formula; it embodies a realm of possibilities within the fields of chemistry and medicine. Its structural features and potential applications make it a compound of interest for scientists and students alike.

Synonyms
23892-33-3
N-(alpha-(p-Chlorophenyl)benzyl)ethylenediamine
ETHYLENEDIAMINE, N-(alpha-(p-CHLOROPHENYL)BENZYL)-
RefChem:345265
DTXSID20946673
N-[(4-CHLOROPHENYL)-PHENYLMETHYL]ETHANE-1,2-DIAMINE
N~1~-[(4-Chlorophenyl)(phenyl)methyl]ethane-1,2-diamine