Interesting facts
Interesting Facts about N-(4-chlorophenyl)acetamide
N-(4-chlorophenyl)acetamide, also known as 4-chloroacetanilide, is a fascinating compound with notable applications and properties. Here are some intriguing insights:
- Pharmaceutical Significance: This compound is often used as an intermediate in the synthesis of various pharmaceutical agents. Its structural similarities to other active compounds make it a key player in drug development.
- Antipyretic Properties: Originally, N-(4-chlorophenyl)acetamide was studied for its potential to act as an antipyretic agent, which means it can help reduce fever. This property has attracted the attention of medicinal chemists.
- Chlorine Substitution: The presence of the chlorine atom in its structure enhances the compound’s lipophilicity, which can influence its biological activities and interactions with enzymes or receptors in living organisms.
- Applications in Organic Chemistry: Beyond its medicinal uses, this compound serves as an essential substrate in organic synthesis, providing a versatile framework for developing new materials and compounds.
- Environmental Impact: As with many chlorinated compounds, there is ongoing research into the environmental persistence and potential toxicity of N-(4-chlorophenyl)acetamide, prompting discussions on safe handling and disposal.
In summary, N-(4-chlorophenyl)acetamide is not just a simple chemical; it embodies a wealth of potential and challenges that intrigue scientists across various fields. As research continues, who knows what exciting new discoveries await us in the study of this compound?
Synonyms
4'-Chloroacetanilide
539-03-7
N-(4-Chlorophenyl)acetamide
4-Chloroacetanilide
P-CHLOROACETANILIDE
N-Acetyl-p-chloroaniline
Acetamide, N-(4-chlorophenyl)-
Acetanilide, 4'-chloro-
N-(p-Chlorophenyl)acetamide
Acetic-4-chloroanilide
N-(4-Chloro-phenyl)-acetamide
NSC 40563
HSDB 1410
N-Acetyl-4-chloroaniline
EINECS 208-707-8
BRN 0509638
6I0LI34G5J
Acetic acid, amide, N(4-chlorophenyl)-
AI3-00509
NSC-444
CHEBI:116915
NSC-40563
DTXSID0060228
P-CHLOROACETANILIDE [HSDB]
4-12-00-01178 (Beilstein Handbook Reference)
N-(4-CHLOROPHENYL)ETHANEAMIDE
PARACETAMOL IMPURITY J [EP IMPURITY]
PARACETAMOL IMPURITY J (EP IMPURITY)
4Chloroacetanilide
Acetic4chloroanilide
NAcetylpchloroaniline
Acetanilide, 4'chloro
N(pChlorophenyl)acetamide
N(4Chlorophenyl)acetamide
Acetamide, N(4chlorophenyl)
DTXCID9041524
Acetic acid, amide, N(4chlorophenyl)
208-707-8
inchi=1/c8h8clno/c1-6(11)10-8-4-2-7(9)3-5-8/h2-5h,1h3,(h,10,11
MFCD00000612
p-Chloroacetoanilide
Acet-p-chloroanilide
N-(4-Chlorophenyl)acetamide (4-Chloroacetanilide)
Paracetamol impurity J
Acetaminophen Impurity J
UNII-6I0LI34G5J
|p|-Chloroacetanilide
4 inverted exclamation marka-Chloroacetanilide
Acetic acid-4-chloroanilide
4'-Chloroacetanilide, 97%
CHEMBL15991
N-(4-chlorophenyl)-acetamide
SCHEMBL197282
NSC444
NSC40563
STR03412
STL419470
TD1001
AKOS003868583
CS-W010786
FC20179
PS-5125
AC-28508
SY012848
A7830
NS00032868
4 inverted exclamation mark -Chloroacetanilide
EN300-79800
10.14272/GGUOCFNAWIODMF-UHFFFAOYSA-N
AE-562/40197438
doi:10.14272/GGUOCFNAWIODMF-UHFFFAOYSA-N
SR-03000001158-1
Q27105138
Z28161730
N-(4-Chlorophenyl)acetamide;N-(p-Chlorophenyl)acetamide;N-Acetyl-4-chloroaniline
Solubility of N-(4-chlorophenyl)acetamide
N-(4-chlorophenyl)acetamide, with the chemical formula C9H10ClN1O1, exhibits interesting solubility characteristics that can be influenced by various factors. Here are some key aspects to consider:
In practical applications, understanding the solubility of this compound is essential for its use in synthesis and formulation. As a note, it’s important to recognize that "like dissolves like" — polar solvents are typically better at dissolving polar compounds, hence the significance of solvent choice in achieving optimal solubility.
Overall, when working with N-(4-chlorophenyl)acetamide, one should carefully consider these factors to effectively manage its solubility for various experimental or industrial purposes.