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N-(4-chlorophenyl)aziridine-1-carboxamide

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Identification
Molecular formula
C9H9ClN2O
CAS number
175008-94-5
IUPAC name
N-(4-chlorophenyl)aziridine-1-carboxamide
State
State

At room temperature, this compound exists as a solid.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
390.50
Boiling point (Kelvin)
663.70
General information
Molecular weight
196.63g/mol
Molar mass
196.6330g/mol
Density
1.2830g/cm3
Appearence

This compound appears as a crystalline solid, often colorless or white, bearing typical properties of organic molecules containing aziridine and aromatic groups.

Comment on solubility

Solubility of N-(4-chlorophenyl)aziridine-1-carboxamide

The solubility of N-(4-chlorophenyl)aziridine-1-carboxamide can vary significantly depending on several factors. While specific empirical data may be limited, we can consider the molecular structure and properties to draw some conclusions.

Factors Influencing Solubility

  • Molecular Structure: The presence of the 4-chlorophenyl group introduces polar characteristics which may enhance solubility in polar solvents.
  • Functional Groups: The carboxamide functional group (-CONH2) is known for its high polar nature, making the compound more soluble in water compared to non-polar solvents.
  • Temperature: Generally, higher temperatures can increase solubility in various solvents.

Given its characteristics, one might expect N-(4-chlorophenyl)aziridine-1-carboxamide to be moderately soluble in polar solvents like water and alcohols, while potentially showing lower solubility in non-polar solvents like hexane.

In summary, understanding the solubility of this compound can be essential for applications in pharmaceuticals and material sciences, making it a subject of interest for further study.

Interesting facts

Interesting Facts about N-(4-chlorophenyl)aziridine-1-carboxamide

N-(4-chlorophenyl)aziridine-1-carboxamide is a fascinating organic compound that belongs to the category of aziridines, which are three-membered nitrogen-containing rings. This compound has garnered attention in various fields of research, particularly due to its unique structural properties and potential applications. Here are some noteworthy aspects:

  • Structure and Reactivity: The aziridine ring is known for its strain, making it highly reactive. This compound's structure allows for interesting *nucleophilic reactions* and *ring-opening reactions*, which opens pathways for synthesizing diverse organic molecules.
  • Pharmaceutical Potential: Compounds like N-(4-chlorophenyl)aziridine-1-carboxamide are studied for their biological activity. Their structural similarities to various bioactive compounds suggest potential therapeutic applications in medicinal chemistry.
  • Research Applications: The compound serves as a valuable intermediate in *synthetic organic chemistry*. Its derivatives may be synthesized to explore their properties and functionalities, providing insights into the development of new materials.
  • Role of Chlorine: The presence of a 4-chlorophenyl group is significant as chlorine substitution can influence both reactivity and biological activity. Chlorinated compounds are often noted for their enhanced *lipophilicity* and altered chemical behavior.
  • Safety Considerations: As with many chemicals, handling N-(4-chlorophenyl)aziridine-1-carboxamide requires precautions. Knowledge of its reactivity and potential hazards is crucial for safe laboratory practices.

In conclusion, N-(4-chlorophenyl)aziridine-1-carboxamide stands out in organic chemistry, offering intriguing possibilities for research and application. Its unique properties encourage further exploration, making it a subject of considerable scholarly interest.

Synonyms
3647-20-9
1-AZIRIDINECARBOXAMIDE, N-(4-CHLOROPHENYL)-
1-Aziridinecarboxamide, N-(p-chlorophenyl)-
1-(1-Aziridinyl)-N-(p-chlorophenyl)formamide
Formamide, 1-(1-aziridinyl)-N-(p-chlorophenyl)-
WLN: T3NTJ AVMR DG
MLS002694001
NSC-76794
NSC 76794
BRN 0146843
AI3-50723
NSC76794
N-(4-Chlorophenyl)-1-aziridinecarboxamide
9J8LAL6DSR
NCIOpen2_000854
CHEMBL1872999
DTXSID90189979
HMS3094K09
AKOS024385690
SMR001559935