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N'-(4-chlorophenyl)benzohydrazide

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Identification
Molecular formula
C13H11ClN2O
CAS number
4569-88-4
IUPAC name
N'-(4-chlorophenyl)benzohydrazide
State
State

At room temperature, N'-(4-chlorophenyl)benzohydrazide is a solid.

Melting point (Celsius)
243.50
Melting point (Kelvin)
516.65
Boiling point (Celsius)
182.50
Boiling point (Kelvin)
455.65
General information
Molecular weight
246.69g/mol
Molar mass
246.6900g/mol
Density
1.3074g/cm3
Appearence

N'-(4-chlorophenyl)benzohydrazide typically appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of N'-(4-chlorophenyl)benzohydrazide

N'-(4-chlorophenyl)benzohydrazide, with its intriguing structure, exhibits specific solubility characteristics that are important to consider:

  • Solvent Interaction: The compound shows limited solubility in polar solvents due to its hydrophobic aromatic rings, making it less favorable for dissolution.
  • Aromatic Characteristics: The presence of multiple aromatic groups typically indicates a reduced solubility in water, aligning with the behavior observed in many similar compounds.
  • Temperature Dependence: Like many organic compounds, the solubility of N'-(4-chlorophenyl)benzohydrazide may increase with temperature, suggesting that heating can enhance dissolution.
  • pH Influence: The solubility may vary with pH, particularly if the compound can be protonated or deprotonated, affecting its interaction with solvents.

In summary, while N'-(4-chlorophenyl)benzohydrazide is expected to have limited solubility in aqueous solutions, its solubility profile can be influenced by various factors such as solvent polarity, temperature, and pH. As with many organic compounds, understanding these aspects can be crucial for developmental and application purposes.

Interesting facts

Interesting Facts about N'-(4-chlorophenyl)benzohydrazide

N'-(4-chlorophenyl)benzohydrazide is a fascinating compound that has garnered attention due to its unique chemical structure and various applications. Here are some compelling points to consider:

  • Structural Insight: This compound features a hydrazide functional group, which is known for its reactivity and versatility in organic synthesis. The presence of a 4-chlorophenyl substituent enhances its electrophilic properties, making it valuable in numerous chemical reactions.
  • Pharmaceutical Applications: N'-(4-chlorophenyl)benzohydrazide has been studied for its potential use in the development of pharmaceuticals. It acts as a building block in the synthesis of several biologically active molecules, thereby playing a crucial role in medicinal chemistry.
  • Potential Biological Activity: Preliminary studies indicate that this compound may possess antimicrobial and antioxidant properties, making it an attractive candidate for further research in the field of therapeutic agents.
  • Versatile Reagent: As a reagent, it is employed in the synthesis of various heterocyclic compounds. Its ability to undergo various reactions, such as condensation and electrophilic aromatic substitution, makes it a helpful tool for synthetic chemists.
  • Research Significance: Numerous research articles have been published detailing the synthetic methods and applications of N'-(4-chlorophenyl)benzohydrazide, contributing to the growing body of work focusing on hydrazide derivatives.

In summary, N'-(4-chlorophenyl)benzohydrazide is not just a simple compound but a valuable asset in the realms of organic chemistry and pharmaceuticals. Its versatility and potential applications make it a subject of interest for ongoing research and development.

Synonyms
BENZOIC ACID, 2-(p-CHLOROPHENYL)HYDRAZIDE
Benzoic (p-chlorophenyl)hydrazide
BRN 0653306
Benzoic acid, 2-(4-chlorophenyl)hydrazide
DTXSID10169894
DTXCID9092385
0-15-00-00428 (Beilstein Handbook Reference)
17473-76-6
N'-(4-chlorophenyl)benzohydrazide
CHEMBL347267
2-(4-Chlorophenyl)hydrazide benzoic acid
BDBM50086489
AKOS000279615
Benzoic acid N''-(4-chloro-phenyl)-hydrazide
SR-01000029130
SR-01000029130-1