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Chlorpheniramine

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Identification
Molecular formula
C16H19ClN2
CAS number
132-22-9
IUPAC name
N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine
State
State

Under standard conditions, chlorpheniramine is in a solid state, appearing as a crystalline powder. It is stable at room temperature.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
270.79g/mol
Molar mass
270.7860g/mol
Density
1.1354g/cm3
Appearence

Chlorpheniramine is typically found as a white to off-white crystalline powder. It may be odorless or possess a slight, characteristic smell.

Comment on solubility

Solubility of N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine

The solubility of N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine can be quite complex due to its unique molecular structure. Understanding its solubility is crucial for various applications in pharmaceuticals and chemical synthesis.

Factors Influencing Solubility

Several factors can influence the solubility of this compound:

  • Polarity: The presence of both hydrophobic chlorophenyl and pyridyl groups contributes to the overall polarity of the molecule.
  • Temperature: As with most organic compounds, increasing the temperature can enhance solubility by providing energy to break intermolecular interactions.
  • Solvent Type: The solubility varies significantly depending on whether the solvent is polar or non-polar, with polar solvents likely allowing for greater solubility.
  • pH Levels: Variations in pH can alter the ionization states of the amine groups, affecting solubility in aqueous solutions.

According to the principle "like dissolves like," this compound may exhibit:
- Higher solubility in organic solvents such as methanol or ethanol
- Limited solubility in water due to the bulky aromatic groups

In summary, while the specific solubility of N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine can vary, it largely depends on factors like polarity, temperature, and the nature of the solvent used. Understanding these aspects is essential for optimizing its use in various chemical contexts.

Interesting facts

Interesting Facts about N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine

N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine is a fascinating compound that has garnered attention in various fields, particularly in medicinal chemistry. Here are some intriguing aspects of this molecule:

  • Pharmaceutical Potential: This compound belongs to a class of compounds known as amine derivatives, which are often explored for their biological activity. Its structural features suggest it could exhibit significant pharmacological properties.
  • Structural Diversity: The presence of both the 4-chlorophenyl group and the 2-pyridyl moiety introduces a degree of molecular complexity. This structural diversity can influence the compound's interactions within biological systems.
  • Targeting Mechanisms: Compounds like this one may interact with specific cellular receptors or enzymes, making them potential candidates for drug development. This opens the door to exploring their role in treating various diseases.
  • Chlorine Substitution: The substitution of a chlorine atom can enhance the compound's lipophilicity, altering its pharmacokinetic properties and potentially increasing its efficacy as a drug.
  • Research Applications: This molecule could serve as a valuable building block for synthesizing other chemical entities, aiding researchers in developing new therapeutic agents.

In summary, N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine exemplifies the intriguing relationship between molecular structure and biological function. As researchers continue to explore its potential, this compound might pave the way for innovative advancements in medicinal chemistry.

Synonyms
Chloropyramine
Halopyramine
Chlorpyramine
59-32-5
Anaphylline
Chlorneoantergan
Suprastin
Avapena
Synopen
Synpen
Chloropyribenzamine
Chlorpyraminum
Allergan S
Synopen R
Chloroneoantergan
Cloropiramina
Chloropyraminum
Chloropyraminum [INN-Latin]
Cloropiramina [INN-Spanish]
NSC 241038
Chloropyramine [INN:BAN:DCF]
UNII-2K3L8O9SOV
EINECS 200-421-1
2K3L8O9SOV
NSC-241038
BRN 0257085
Chloropyramine (INN)
N-(p-Chlorobenzyl)-N',N'-dimethyl-N-(2-pyridyl)ethylenediamine
2-((p-Chlorobenzyl)(2-(dimethylamino)ethyl)amino)pyridine
CHLOROPYRAMINE [MI]
CHLOROPYRAMINE [INN]
Ethylenediamine, N-(p-chlorobenzyl)-N',N'-dimethyl-N-(2-pyridyl)-
2-((p-Chlorobenzyl)(2-dimethylaminoethyl)amino)pyridine
CHLOROPYRAMINE [WHO-DD]
p-Chlorbenzyl-alpha-pyridyl-dimethyl-aethylendiamin [German]
Pyridine, 2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-
DTXSID50207729
4-22-00-03928 (Beilstein Handbook Reference)
p-Chlorbenzyl-alpha-pyridyl-dimethyl-aethylendiamin
1,2-Ethanediamine, N-((4-chlorophenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-
1,2-Ethanediamine, N-[(4-chlorophenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-
NSC241038
p-Chlorbenzyl-.alpha.-pyridyl-dimethyl-aethylendiamin
Avapena (TN)
N-(4-Chlorobenzyl)-N',N'-dimethyl-N-(pyridin-2-yl)ethane-1,2-diamine
Chloropyraminum (INN-Latin)
Cloropiramina (INN-Spanish)
2-[(p-Chlorobenzyl)[2-(dimethylamino)ethyl]amino]pyridine
N,N-Dimethyl-N'-(p-chlorobenzyl)-N'-(2-pyridyl)ethylenediamine
N-[(4-chlorophenyl)methyl]-N-[2-(dimethylamino)ethyl]pyridin-2-amine
Pyridine, 2-[(p-chlorobenzyl)[2-(dimethylamino)ethyl]amino]-
N-((4-chlorophenyl)methyl)-N-(2-(dimethylamino)ethyl)pyridin-2-amine
D04AA09
DTXCID50130220
R06AC03
N-(p-chlorobenzyl)-N-(2-pyridyl)-N',N''-dimethylethylenediamine
1,2-Ethanediamine, N-((4-chlorophenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-(9CI)
200-421-1
ickffnbdfnzjsx-uhfffaoysa-n
N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
NCGC00016672-01
NCGC00016672-04
CAS-6170-42-9
FAK inhibitor C4
Prestwick0_000807
Prestwick1_000807
Prestwick2_000807
Prestwick3_000807
SCHEMBL30021
BSPBio_000673
SPBio_002594
BPBio1_000741
CHEMBL1194287
CHEBI:94767
GLXC-15649
STL483421
AKOS024323312
WLN: T6NJ BN2N1&1&1R DG
DB08800
NCGC00016672-02
NCGC00016672-07
DA-72178
SBI-0207051.P001
HY-119995
CS-0078886
NS00034133
D07195
Q729863
2-[(p-Chlorobenzyl)[2-(dimethylamino)ethyl]pyridine
BRD-K83257731-003-03-7
BRD-K83257731-003-14-4
BRD-K83257731-003-23-5
1, N-[(4-chlorophenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-
N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridinyl)ethane-1,2-diamine
N-((4-CHLOROPHENYL)METHYL)-N',N'-DIMETHYL-N-2-PYRIDINYL-1,2-ETHANEDIAMINE
N\'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N\'-pyridin-2-ylethane-1,2-diamine