N'-(4-chlorophenyl)pyridine-4-carboxamidine

Identification

Molecular formula

C₁₂H₁₀ClN₃

CAS number

NULL

IUPAC name

N'-(4-chlorophenyl)pyridine-4-carboxamidine

State

At room temperature, N'-(4-chlorophenyl)pyridine-4-carboxamidine is generally in a solid state, specifically as a crystalline powder or solid.

Melting point (Celsius)

258.00

Melting point (Kelvin)

531.15

Boiling point (Celsius)

404.00

Boiling point (Kelvin)

677.15

General information

Molecular weight

244.69g/mol

Molar mass

244.6890g/mol

Density

1.3400g/cm³

Appearence

N'-(4-chlorophenyl)pyridine-4-carboxamidine typically appears as a crystalline solid. The compound is characterized by its off-white to light tan color, depending on purity and specific synthesis methods used.

Comment on solubility

Solubility of N'-(4-chlorophenyl)pyridine-4-carboxamidine

N'-(4-chlorophenyl)pyridine-4-carboxamidine is an interesting compound with unique solubility characteristics that can be influenced by various factors:

Polarity: The presence of both a pyridine ring and a carboxamidine functional group generally contributes to the polar nature of the molecule, enhancing its solubility in polar solvents.
Solvent Type: This compound is likely to be soluble in polar aprotic solvents such as DMSO or DMF, which can effectively interact with the polar regions of the molecule.
Temperature Dependency: As with many organic compounds, solubility can increase with temperature. Higher temperatures often provide more kinetic energy, promoting solvation processes.
pH Sensitivity: Being a carboxamidine, the solubility may also depend on the pH of the solution. It is possible that changes in pH could alter the protonation state of the amine, affecting solubility.

In general, while N'-(4-chlorophenyl)pyridine-4-carboxamidine is expected to possess moderate to good solubility in suitable solvents, the specific conditions should be carefully considered when predicting its behavior in different environments.

Interesting facts

Interesting Facts about N'-(4-chlorophenyl)pyridine-4-carboxamidine

N'-(4-chlorophenyl)pyridine-4-carboxamidine is a unique compound that captures the attention of chemists and researchers alike. This compound belongs to the class of carboxamidine derivatives, which are known for their versatile applications in various fields. Here are some intriguing insights about this specific compound:

Pharmaceutical Potential: Compounds similar to N'-(4-chlorophenyl)pyridine-4-carboxamidine have shown significant promise in medicinal chemistry. They may exhibit various biological activities, including anti-inflammatory and anticancer properties, making them a subject of interest in drug discovery.
Synthetic Versatility: The ability to modify the aromatic rings in this compound allows for the synthesis of a range of analogs. This feature enables researchers to explore and fine-tune the pharmacological profiles of these derivatives.
Aromatic Properties: The presence of the ⁴-chlorophenyl group enhances the compound's stability and hydrophobic interactions, which can play a crucial role in its activity and reactivity.
Research Interest: The compound is often studied in the context of organic synthesis and medicinal chemistry, making it a valuable topic for students interested in these fields. Its complex structure provides numerous avenues for research and experimental exploration.

The study of N'-(4-chlorophenyl)pyridine-4-carboxamidine not only illustrates the beauty of chemical synthesis but also emphasizes the ongoing quest for innovative solutions in pharmaceuticals. As one researcher aptly put it, "The journey into the world of carboxamidines is much like navigating through a labyrinth of potential discoveries." This compound is a testament to the endless possibilities within the field of chemistry.

Synonyms

N-(p-Chlorophenyl)isonicotinamidine

ISONICOTINAMIDINE, N-(p-CHLOROPHENYL)-

BRN 0476710

23565-10-8

4-Pyridinecarboximidamine, N-(4-chlorophenyl)-

DTXSID90178186

RefChem:349660

DTXCID20100677