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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[4-(diethylamino)phenyl]acetamide
State
State

At room temperature, Lidocaine is typically in a solid state as a crystalline powder. It is stable under normal conditions of storage and handling.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0060g/cm3
Appearence

Lidocaine appears as a white or off-white crystalline powder. It may exhibit some hygroscopic properties, meaning it can absorb moisture from the air. It is odorless and has a bitter taste.

Comment on solubility

Solubility of N-[4-(diethylamino)phenyl]acetamide

N-[4-(diethylamino)phenyl]acetamide, often referenced in chemical literature, presents interesting solubility characteristics. Understanding its solubility is essential, particularly for applications in pharmaceuticals and organic synthesis.

  • Polarity: The presence of both an amide group and diethylamino moiety contributes to its overall molecular polarity, affecting its solubility in various solvents.
  • Aqueous Solubility: N-[4-(diethylamino)phenyl]acetamide is expected to have limited solubility in water, primarily due to its organic nature and larger hydrophobic structures.
  • Organic Solvents: It likely dissolves well in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), making it suitable for reactions and solutions requiring non-polar to moderately polar environments.

In summary, the solubility of N-[4-(diethylamino)phenyl]acetamide is quite versatile, being particularly favorable in non-aqueous solvents while more limited in polar solvents like water. As with many organic compounds, the specific conditions like temperature and the presence of other solutes can further influence its solubility profile.

Interesting facts

Interesting Facts about N-[4-(diethylamino)phenyl]acetamide

N-[4-(diethylamino)phenyl]acetamide, commonly known as a chemical compound that plays a significant role in various scientific applications, is fascinating not only due to its structure but also its versatility in the field of organic chemistry.

Key Features

  • Structure and Function: This compound contains a diethylamino group which enhances its solubility and reactivity, making it valuable in numerous chemical reactions.
  • Applications: It is prominently used in medicinal chemistry as an intermediate for the synthesis of pharmaceutical agents. Its ability to affect biological systems underscores its medicinal potential.
  • Colorimetric Properties: The presence of the aromatic ring contributes to its colorimetric properties, which can be beneficial in various analysis and detection methods.

Research Significance

Researchers are particularly interested in exploring the various derivatives of N-[4-(diethylamino)phenyl]acetamide as potential candidates in drug discovery. Studies have shown that modifications to this compound can lead to enhanced pharmacological effects, making this compound an exciting subject of investigation.

Quote from a Chemist

As a prominent figure in drug design states, "The beauty of synthetic chemistry lies in our ability to modify simple structures into complex molecules that can have profound effects on human health." This captures the essence of what makes N-[4-(diethylamino)phenyl]acetamide and similar compounds compelling to study.

In summary, N-[4-(diethylamino)phenyl]acetamide is not just a simple molecule; it is a gateway into the broader world of medicinal chemistry and organic synthesis, paving the way for innovative therapeutic solutions.

Synonyms
N-(4-(Diethylamino)phenyl)acetamide
5326-57-8
4'-Diethylaminoacetanilide
N-[4-(Diethylamino)phenyl]acetamide
p-Diethylaminoacetanilide
ACETANILIDE, 4'-(DIETHYLAMINO)-
p-(Diethylamino)acetanilide
Acetamide, N-(4-(diethylamino)phenyl)-
4-Diethylaminoacetanilide
JE3YD7DJR5
NSC-4037
Acetamide, N-[4-(diethylamino)phenyl]-
NSC 4037
BRN 2372601
AI3-15488
ACETAMIDE,N-(4-(DIETHYLAMINO)PHENYL)-
NSC4037
MFCD00026713
UNII-JE3YD7DJR5
Acetamide, N-(4-(diethylamino)phenyl)- (9CI)
Oprea1_325431
WLN: 2N2&R DMV1
N-acetyl-4-diethylaminoaniline
F0347-1457
SCHEMBL4950655
DTXSID30201381
AKOS001485872
4-ACETYLAMINO-N,N-DIETHYLANILINE
N-[4-(Diethylamino)phenyl]acetamide #
P-(ACETAMIDO)-N,N-DIETHYLANILINE
AS-30247
CS-0317662
NS00123388
N-DIETHYL-N'-ACETYL-P-PHENYLENEDIAMINE
1,4-Benzenediamine, N-acetyl-N',N'-diethyl-
AB00090981-01
N,N-DIETHYL-N'-ACETYL-P-PHENYLENEDIAMINE
SR-01000410706
SR-01000410706-1