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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[4-(dimethylamino)but-2-ynyl]-N-methyl-acetamide
State
State

At room temperature, Lidocaine is typically found as a solid when in its pure form. It can also be formulated into a liquid or gel for medical use.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3440g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white, crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of N-[4-(dimethylamino)but-2-ynyl]-N-methyl-acetamide

The solubility of N-[4-(dimethylamino)but-2-ynyl]-N-methyl-acetamide is a topic of interest for many researchers due to its unique chemical structure and potential applications. Understanding its solubility characteristics is crucial for effectively utilizing this compound in various chemical processes. Here are some key points to consider:

  • Solvent Compatibility: This compound is generally more soluble in polar solvents such as water or alcohols. The presence of the dimethylamino group can enhance solubility in aqueous mediums.
  • Temperature Dependence: Solubility may increase with temperature, leading to improved dissolution rates; hence, it is advisable to conduct experiments at elevated temperatures.
  • Acidity and Basicity: The presence of amide groups tends to increase solubility in acidic or basic solutions, which can facilitate the dissolution process.

It is important to note that the specific solubility characteristics can vary based on factors such as:

  1. Concentration of the compound
  2. Purity of solvents used
  3. Presence of ionic or non-ionic species in the solution

In summary, the solubility of N-[4-(dimethylamino)but-2-ynyl]-N-methyl-acetamide is influenced by its chemical structure and environmental factors. Careful consideration of these elements will guide researchers in their use of this compound.

Interesting facts

Interesting Facts about N-[4-(dimethylamino)but-2-ynyl]-N-methyl-acetamide

N-[4-(dimethylamino)but-2-ynyl]-N-methyl-acetamide is a fascinating compound that delves into the realms of organic chemistry and medicinal applications. Here are some intriguing aspects:

  • Structural Complexity: This compound showcases a unique structure, characterized by its multiple functional groups, which contribute to its reactivity and interactions.
  • Role in Pharmaceuticals: Compounds like N-[4-(dimethylamino)but-2-ynyl]-N-methyl-acetamide can serve as critical intermediates in the synthesis of various pharmaceuticals. Their intricate structure opens doors to innovative drug development.
  • Dimethylamino Group: The presence of the dimethylamino group is noteworthy, as it enhances the compound's solubility in organic solvents, significantly impacting its biological activity.
  • Alkynyl Component: The alkynyl segment introduces specific alkyne reactivity, which chemists can exploit for various reactions, including cycloadditions and other polymerization processes.
  • Behavior in Biology: Research suggests that compounds with similar structural motifs can exhibit interesting interactions with biological targets, making them potential candidates for further studies in drug efficacy and mechanism of action.

In summary, N-[4-(dimethylamino)but-2-ynyl]-N-methyl-acetamide exemplifies the interplay between structure and function in chemistry. Its potential applications in medicinal chemistry and organic synthesis render it a compound of considerable interest.

Synonyms
18327-42-9
N-(4-Dimethylamino-but-2-ynyl)-N-methyl-acetamide
CHEMBL75358
N-[4-(dimethylamino)but-2-ynyl]-N-methylacetamide
SCHEMBL11727547
DTXSID20274645
BDBM50009291
PD186899