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N-(4-ethoxy-3-nitro-phenyl)acetamide

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Identification
Molecular formula
C10H12N2O4
CAS number
41392-97-4
IUPAC name
N-(4-ethoxy-3-nitro-phenyl)acetamide
State
State

At room temperature, N-(4-ethoxy-3-nitro-phenyl)acetamide is a solid. It is typically stable under normal conditions of use and storage.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
224.21g/mol
Molar mass
224.2200g/mol
Density
1.3880g/cm3
Appearence

N-(4-ethoxy-3-nitro-phenyl)acetamide appears as a pale yellow crystalline solid. It might also have a faint odor, characteristic of organic nitro compounds. The appearance is indicative of its chemical structure and the presence of nitro and ethoxy functional groups.

Comment on solubility

Solubility of N-(4-ethoxy-3-nitro-phenyl)acetamide

N-(4-ethoxy-3-nitro-phenyl)acetamide is a compound characterized by its unique functional groups, which can significantly influence its solubility. Understanding the solubility behavior of this compound is essential for its applications in various fields, including pharmaceuticals and materials science. Here are some key points to consider:

  • Polarity: The presence of both the ethoxy and nitro groups introduces polar characteristics to the compound, impacting its ability to dissolve in polar solvents like water.
  • Solvents: It is more likely to be soluble in organic solvents such as ethanol, methanol, and acetone, which can effectively interact with its functional groups.
  • Hydrogen Bonding: The acetamide moiety may enable hydrogen bonding, facilitating solubility in certain solvents.
  • Temperature Dependency: Solubility often increases with temperature; thus, heating may enhance the dissolution of N-(4-ethoxy-3-nitro-phenyl)acetamide in relevant solvents.
  • pH Effects: The solubility can be affected by the pH of the solution, particularly if the compound is ionizable in basic or acidic conditions.

In summary, while N-(4-ethoxy-3-nitro-phenyl)acetamide may show variable solubility depending on several factors, it is generally expected to be more soluble in organic solvents than in water. Understanding these solubility characteristics is crucial for optimizing its use in practical applications.

Interesting facts

Interesting Facts about N-(4-ethoxy-3-nitro-phenyl)acetamide

N-(4-ethoxy-3-nitro-phenyl)acetamide is a fascinating compound that has piqued the interest of chemists and researchers alike. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: Research suggests that compounds similar to N-(4-ethoxy-3-nitro-phenyl)acetamide often exhibit valuable biological activities. This could potentially allow for applications in the development of pharmaceuticals.
  • Characteristic Functional Groups: The presence of an ethoxy group and a nitro group in this compound plays a critical role in its reactivity and stability. Functional groups can significantly influence the chemical behavior, including solubility and polarity.
  • Versatile Synthesis: The synthesis of N-(4-ethoxy-3-nitro-phenyl)acetamide may involve various methods, showcasing the flexibility of synthetic organic chemistry. Understanding different synthetic routes can help students and chemists explore alternatives for producing similar compounds.
  • Analogous Compounds: This compound belongs to a larger family of acetamides. Many acetamides display interesting characteristics, making them important in agrochemical and pharmaceutical applications.
  • Subjects of Study: In the academic realm, N-(4-ethoxy-3-nitro-phenyl)acetamide can be utilized for teaching organic synthesis, functional group transformation, and reaction mechanisms, offering valuable practical experience to students.

In conclusion, N-(4-ethoxy-3-nitro-phenyl)acetamide serves not only as a compelling subject in organic chemistry but also as a stepping stone for understanding more complex chemical systems. Its potential applications in medicinal chemistry continue to inspire research and exploration in the field.

Synonyms
N-(4-Ethoxy-3-nitrophenyl)acetamide
3-Nitro-p-acetophenetide
3'-NITRO-P-ACETOPHENETIDIDE
3-Nitro-P-acetophenetidide
Acetamide, N-(4-ethoxy-3-nitrophenyl)-
CCRIS 439
HSDB 4116
EINECS 217-211-0
UNII-F1EYM62K39
BRN 2735844
DTXSID5020942
3-13-00-01202 (Beilstein Handbook Reference)
3'-NITRO-P-ACETOPHENETIDIDE [HSDB]
3Nitropacetophenetide
5Nitropacetophenetidide
2Nitro4acetaminofenetol
3'Nitropacetophenetidin
4Acetamino2nitrophenetole
pAcetophenetidide, 3'nitro
DTXCID30942
p-Acetophenetide, 3'-nitro-
N(4Ethoxy3nitro)phenylacetamide
N(4Ethoxyphenyl)3'nitroacetamide
Acetamide, N(4ethoxy3nitrophenyl)
4Ethoxy3nitroanilid kyseliny octove
4-ACETAMINO-2-NITRO-PHENETOLE
uoipfpsgiawjaq-uhfffaoysa-n
1777-84-0
3'-Nitro-p-acetophenetide
5-Nitro-p-acetophenetidide
4-Acetamino-2-nitrophenetole
3'-Nitro-p-acetophenetidin
p-Acetophenetidide, 3-nitro-
N-(4-Ethoxy-3-nitro)phenylacetamide
N-(4-Ethoxyphenyl)-3'-nitroacetamide
p-Acetophenetidide, 3'-nitro-
NCI-C01978
2-Nitro-4-acetaminofenetol
4-Ethoxy-3-nitroanilid kyseliny octove
F1EYM62K39
3-Nitro-4-ethoxy-N-acetylaniline
N-[4-(ethyloxy)-3-nitrophenyl]acetamide
2-Nitro-4-acetaminofenetol [Czech]
4-Ethoxy-3-nitroanilid kyseliny octove [Czech]
nitro-4-acetaminophenetole
Cambridge id 5211946
Oprea1_496377
Oprea1_796781
MLS000712720
CHEMBL1563395
SCHEMBL11316740
HMS2670A18
STL181338
AKOS000592921
NCGC00245080-01
SMR000282487
NS00025862
Q27277512