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N-(4-ethoxyphenyl)-2-iodoacetamide

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Identification
Molecular formula
C10H12INO2
CAS number
142320-59-4
IUPAC name
N-(4-ethoxyphenyl)-2-iodo-acetamide
State
State
At room temperature, N-(4-ethoxyphenyl)-2-iodoacetamide is a solid compound. It is typically found as a crystalline solid, making it easy to handle and measure in laboratory settings.
Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
294.00
Boiling point (Kelvin)
567.15
General information
Molecular weight
307.10g/mol
Molar mass
307.1030g/mol
Density
1.6712g/cm3
Appearence
N-(4-ethoxyphenyl)-2-iodoacetamide is generally a crystalline solid that has a slight to moderate yellow coloration. Light exposure might result in changes to the color due to the presence of the iodine group within the compound. Its crystalline nature means it forms solid structures with a uniform geometric shape at a microscopic level.
Comment on solubility

Solubility of N-(4-ethoxyphenyl)-2-iodo-acetamide

N-(4-ethoxyphenyl)-2-iodo-acetamide is an interesting compound when it comes to its solubility properties. Understanding the solubility of this compound is crucial for its application in various fields such as pharmaceuticals and material science. Here’s a detailed look at its solubility characteristics:

  • Solvent Compatibility: The solubility of N-(4-ethoxyphenyl)-2-iodo-acetamide can vary significantly depending on the solvent used. It is generally more soluble in organic solvents due to its hydrophobic ethoxy and aromatic groups.
  • Hydrophilicity vs. Hydrophobicity: The presence of the ethoxy group provides a degree of hydrophilicity, which may improve its solubility in polar solvents compared to purely hydrophobic compounds.
  • Temperature Influence: Like many organic compounds, temperature can play a role in its solubility. Increased temperature typically enhances solubility, allowing for a greater dispersion of the compound in the solvent.
  • Concentration Effects: At higher concentrations, the solubility may become limited, and precipitation can occur, resulting in a saturation point that must be carefully monitored in experiments.

In summary, it’s essential to consider these factors when evaluating the solubility of N-(4-ethoxyphenyl)-2-iodo-acetamide for practical applications. This compound demonstrates a balance between hydrophilic and hydrophobic characteristics, making it versatile in various experimental contexts.

Interesting facts

Interesting Facts about N-(4-ethoxyphenyl)-2-iodo-acetamide

N-(4-ethoxyphenyl)-2-iodo-acetamide is a fascinating compound with diverse applications in the fields of medicinal chemistry and organic synthesis. Here are some interesting highlights about this intriguing compound:

  • Pharmaceutical Potential: This compound belongs to a class of derivatives that can have potential as pharmaceutical agents. The incorporation of the iodo group often enhances biological activity, making these compounds valuable in drug design.
  • Structure and Properties: The presence of an ethoxy group adds significant steric and electronic effects, which can influence reactivity and interaction with biological targets.
  • Synthetic Routes: N-(4-ethoxyphenyl)-2-iodo-acetamide can be synthesized through various methods involving electrophilic aromatic substitution reactions, serving as an excellent example of modern synthetic organic chemistry techniques.
  • Research Applications: This compound is often used in research, particularly in studying tumor activity and cellular processes because of its selective targeting capabilities.
  • Mechanistic Insights: Understanding the mechanisms of action of such compounds can result in significant breakthroughs in developing new therapies for diseases.
  • Environmental Relevance: Halogenated compounds like this one can sometimes be found in environmental studies, offering insights into pollution and the behavior of chemicals in the ecosystem.

In conclusion, N-(4-ethoxyphenyl)-2-iodo-acetamide represents an exciting component of contemporary chemical research with the potential to make waves in the pharmaceutical industry. As our understanding of such compounds deepens, we may uncover even more opportunities for innovation and therapeutic advancements.

Synonyms
17641-13-3
2-Iodo-p-acetophenetidide
p-ACETOPHENETIDIDE, 2-IODO-
N-(Iodoacetyl)-p-phenetidide
p-Phenetidine, N-(iodoacetyl)-
BRN 2721688
DTXSID20170133
DTXCID9092624
N-(4-ethoxyphenyl)-2-iodoacetamide
Jodphenacetin
AKOS014115890
A1-05991