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Paracetamol Hydroxamic Acid

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Identification
Molecular formula
C10H13NO3
CAS number
63932-29-4
IUPAC name
N-(4-ethoxyphenyl)-N-hydroxy-acetamide
State
State
At room temperature, Paracetamol Hydroxamic Acid exists as a solid. It holds its form well under ambient conditions, maintaining the crystalline structure.
Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
247.00
Boiling point (Kelvin)
520.15
General information
Molecular weight
195.22g/mol
Molar mass
195.2210g/mol
Density
1.2944g/cm3
Appearence

Paracetamol Hydroxamic Acid typically appears as a white to off-white crystalline solid. Its form in solid state is fine powdery, and it is known for its characteristic crystalline sheen.

Comment on solubility

Solubility of N-(4-ethoxyphenyl)-N-hydroxy-acetamide

N-(4-ethoxyphenyl)-N-hydroxy-acetamide is a compound with interesting solubility characteristics due to its hydrophilic and hydrophobic components. Understanding the solubility behavior of this compound involves several factors:

  • Polarity: The presence of the hydroxy group (-OH) contributes to the compound's overall polarity, promoting solubility in polar solvents such as water.
  • Hydrophobic interactions: The ethoxyphenyl group imparts a hydrophobic character, which may limit solubility in non-polar solvents.
  • Temperature effects: Solubility can be influenced by temperature; generally, an increase in temperature may enhance solubility in both polar and non-polar solvents.

As a result, N-(4-ethoxyphenyl)-N-hydroxy-acetamide may display moderate solubility in various organic solvents and strong solubility in polar environments, reflecting the balance between its hydrophobic and hydrophilic properties. Researchers looking to utilize this compound will need to consider these solubility factors when selecting solvents for reactions or applications.

In summary, the solubility profile of N-(4-ethoxyphenyl)-N-hydroxy-acetamide can be characterized by:

  1. Potential for high solubility in polar solvents due to hydrophilicity.
  2. Limited solubility in non-polar solvents driven by hydrophobic effects.
  3. Temperature-dependent behavior influencing overall solubility.
Interesting facts

Discovering N-(4-ethoxyphenyl)-N-hydroxy-acetamide

N-(4-ethoxyphenyl)-N-hydroxy-acetamide is a fascinating compound that merges various chemical functionalities into one intriguing structure. Here are some interesting aspects worth exploring:

  • Biological Relevance: This compound has been investigated for its potential *biological activities*, particularly in relation to its anti-inflammatory and analgesic properties. Scientists are increasingly interested in compounds that can provide therapeutic benefits with fewer side effects.
  • Mechanism of Action: Some studies suggest that compounds like N-(4-ethoxyphenyl)-N-hydroxy-acetamide can modulate specific biochemical pathways, making them potential candidates for drug development. Understanding these mechanisms is crucial in pharmacology.
  • Challenges in Synthesis: The synthesis of this compound involves various organic reactions, and chemists often face challenges related to yields and purity. The reaction conditions must be optimized to achieve the desired product efficiently.
  • Structure Activity Relationship (SAR): This compound's structure complements its activity profile, and researchers commonly explore *SARs* to determine how modifications in the molecular structure can impact biological activity. Such studies help in designing more effective agents.
  • Interdisciplinary Applications: The study of N-(4-ethoxyphenyl)-N-hydroxy-acetamide encompasses several fields, including medicinal chemistry, organic synthesis, and pharmacology. This interplay highlights the importance of collaborative research in advancing our understanding of complex compounds.

In conclusion, N-(4-ethoxyphenyl)-N-hydroxy-acetamide is more than just a chemical entity; it represents a wealth of potential opportunities for scientific discovery and innovation. The future of such compounds holds promise for *novel therapies* aimed at enhancing human health.

Synonyms
N-Hydroxyphenacetin
N-(4-Ethoxyphenyl)-N-hydroxyacetamide
19315-64-1
Acetamide, N-(4-ethoxyphenyl)-N-hydroxy-
N-Hydroxy-p-acetophenetidide
Acetohydroxamic acid, N-(p-ethoxyphenyl)-
BX808PYL73
NSC-229647
DTXSID80172916
DTXCID6095407
RefChem:163556
p-Acetophenetidide, N-hydroxy-
N-(4-Ethoxyphenyl)acetohydroxamic acid
ACETOHYDROXAMIC ACID, N-(4-ETHOXYPHENYL)-
CCRIS 339
N-(p-Ethoxyphenyl)acetohydroxamic acid
NSC 229647
BRN 2104196
UNII-BX808PYL73
HYDROXYPHENACETIN, N-
SCHEMBL3279381
GPMYDZBSYQUDJZ-UHFFFAOYSA-N
NSC229647
4'-ETHOXY-N-HYDROXYACETANILIDE
AKOS006272871
N-(4-Ethoxyphenyl)-N-hydroxyacetamide #
NS00115924