Skip to main content

Azaperone

ADVERTISEMENT
Identification
Molecular formula
C18H22N4O
CAS number
1649-18-9
IUPAC name
N-(4-ethyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-3,5-dimethyl-pyrazole-1-carboxamide
State
State

At room temperature, azaperone is typically found as a solid powder. In its pure form, it is stable, although solutions may be prepared for application in various fields such as veterinary medicine.

Melting point (Celsius)
149.00
Melting point (Kelvin)
422.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
327.45g/mol
Molar mass
327.4540g/mol
Density
1.2000g/cm3
Appearence

Azaperone appears as a white crystalline powder. It is often used in its salt form which can dissolve in water, typically forming a clear solution. The compound is odorless and has a bitter taste.

Comment on solubility

Solubility of N-(4-ethyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-3,5-dimethyl-pyrazole-1-carboxamide

The solubility of N-(4-ethyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-3,5-dimethyl-pyrazole-1-carboxamide can be influenced by various factors, including its structural complexity and molecular interactions. Here are some key points to consider:

  • Polarity: The compound exhibits significant polarity due to the presence of functional groups, which may enhance its solubility in polar solvents such as water and alcohols.
  • Hydrophobic interactions: The hexahydroindole structure contributes to hydrophobic characteristics, potentially limiting its solubility in highly polar solvents.
  • pH dependency: The solubility may also vary with pH, especially if the compound possesses acidic or basic functional groups that can ionize.
  • Temperature effects: Increased temperature can enhance solubility for many organic compounds; however, specific behaviors should be characterized through empirical data.

In practice, it is often observed that complex organic molecules like this one may have limited solubility in aqueous environments despite favorable attributes. To illustrate, "Like dissolves like" applies, suggesting that non-polar compounds dissolve well in non-polar solvents, potentially impacting formulation options for this compound in pharmaceutical contexts.

In summary, the solubility profile of N-(4-ethyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-3,5-dimethyl-pyrazole-1-carboxamide will depend heavily on its interactions with the solvent matrix and environmental conditions.

Interesting facts

Interesting Facts About N-(4-Ethyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-3,5-dimethyl-pyrazole-1-carboxamide

This compound, with its *intriguing structure*, belongs to a class of molecules that have garnered attention due to their potential biological activities. Here are some interesting points about this fascinating compound:

  • Pharmacological Potential: Many derivatives of pyrazole and indole-based compounds are known for their diverse therapeutic properties. This particular compound may exhibit *bioactivity* that could be beneficial in drug development.
  • Structural Complexity: The unique *hexahydroindolo* structure attached to a pyrazole backbone introduces a complex three-dimensional shape, which can influence its interactions with biological targets.
  • Medicinal Chemistry: The combination of various functional groups in the compound suggests potential for *synergistic effects*, which can enhance therapeutic efficacy when targeting specific disease pathways.
  • Research Applications: Compounds like this one are often used in *medicinal chemistry research*, providing insights into structure-activity relationships (SAR) that are critical for advancing drug discovery.
  • Historical Context: The study of pyrazole derivatives has a rich history, with compounds originally gaining attention in the early 20th century and evolving into an important focus within modern pharmacology.

In conclusion, N-(4-ethyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-3,5-dimethyl-pyrazole-1-carboxamide stands as a testament to the versatility of chemical compounds in medicinal applications. As research continues, who knows what therapeutic potential this compound may unveil?

Synonyms
Pyrazole-1-carboxamide, N-(4-ethyl-4,6,6a,7,8,9,10,10a-octahydro-7-methylindolo[4,3-fg]quinolin-9-yl)-3,5-dimethyl-
SCHEMBL635775
DTXSID80864006
NS00127330
N-(1-Ethyl-6-methylergolin-8-yl)-3,5-dimethyl-1H-pyrazole-1-carboxamide